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Author: Arkana Author

Membranous Glomerulopathy Subtyping

The diagnosis of membranous glomerulopathy has evolved rapidly in the past 10 years since the identification of PLA2R as the major target antigen in primary membranous glomerulopathy. Today, rather than subtyping into vague categories such as 'primary' and 'secondary', we have tools available to name the specific type of disease present in most cases. Arkana Laboratories offers diagnostic testing for membranous glomerulopathy including immunohistochemical stains for tissue typing of PLA2R, THSD7A, EXT1/2, and NELL1 membranous and serum testing to monitor disease in patients with PLA2R and THSD7A-associated membranous glomerulopathy.  

Fellowing Joel: Episode 7

[video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/Fellowing-Joel-Ep-7.mp4"][/video] This week we caught Dr. Murphy behind the scope with Dr. Kuperman as he was asked to explain his diagnosis of a tricky case.    

Endocarditis-Associated Glomerulonephritis

The patient is a 45-year-old IV drug user who presents with fevers, chills, hematuria, and fatigue. On laboratory testing, he was found to have a creatinine of 4.8. Complement levels are depressed and blood cultures are positive. A transesophageal echocardiogram confirmed the presence of endocarditis. A kidney biopsy was obtained due to hematuria. Image 1 and Image 3 shows circumferential cellular crescents with fibrinoid necrosis (many intracapillary neutrophils are seen in image 3). Figure 2 shows severe interstitial fibrosis. Images 4 and 5 show immunofluorescence staining with IgM and C3, respectively. This is a case of endocarditis-associated glomerulonephritis with diffuse...

River the Office Dummy

Last week Gail pulled her dummy from the closet (he goes by River around here) to set him up as someone taking a nap in the common space. Since then, River has entertained a visitor... Caught up on some reading... And started to plan his Halloween costume!  He's really been checking things off of his to-do list this past week.    

Arkana Employee Spotlight: Kaleigh

Meet Kaleigh Miskin. Kaleigh is a cytologist and histologist who joined our lab in 2015.  She received her cytotech degree from University of Arkansas for Medical Sciences in 2015 and became a licensed histotechnologist in 2017. Her knowledge, ability, and attitude led to her promotion to Assistant Lead in the Light Microscopy section of our laboratory in 2018.  Co-workers describe Kaleigh as kind, positive, organized and patient. She leads by example and is quick to jump in to help without complaint. Likewise, Kaleigh says her favorite part about working at Arkana is the environment. "There are nice people, we get...

Fellowing Joel: Episode 5

This week Dr. Murphy learned a lesson in Arkana culture.  [video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/IMG_1387-1.mp4"][/video]

Fellowing Joel: Episode 4

[video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/IMG_1387.mp4"][/video] This week we caught Dr. Murphy while learning our EM process.    

Fellowing Joel: Episode 3

[video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/Fellowing-Joel_Episode-3.mp4"][/video] It's Friday, and we caught up with Dr. Murphy to see what he has been learning all week! The kidney art on the screen as illustrated by the talented Dr. Stephen Bonsib.    

Fellowing Joel: Episode 2

Today is Friday! That means it's time to see what our renal fellow, Dr. Murphy, has been learning. [video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/Fellowing_Joel_Ep_2.mp4"][/video]    

Fellowing Joel: Episode 1

This summer Dr. Joel Murphy (@md_murph) started as a fellow here at Arkana. For the remainder of his fellowship, we will be following his journey in a weekly video series called Fellowing Joel! [video width="1920" height="1080" mp4="https://www.arkanalabs.com/wp-content/uploads/Fellowing-Joel-Ep-1-FINAL.mp4"][/video]