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Toxic Vacuolar Myopathy Due to Hydroxychloroquine
Clinical History:This 50-year-old patient presented with a one year history of of persistent muscle weakness. They also had shortness of…
Sporadic Late-Onset Nemaline Myopathy
Clinical History:The patient is a 69-year-old male who presented with complaints of proximal lower extremity muscle weakness and BMI of…
Lipid Storage Myopathy in 77-Year-Old Patient
Clinical History:The patient is a 77-year-old female with several months of progressive muscle weakness predominantly in her upper and lower…
2025 Holiday Party: A Very Arkana Christmas
On December 6, the Arkana team celebrated the holiday season at Southern Tail Brewing with friends and family for “A…
Vasculitic Neuropathy
Clinical History:65-year-old woman with generalized weakness and fatigue requiring a walker.Past medical history: anemia, major depressive disorder, MCI, arthritis, CTS,…
Anti-TIF1-γ in Dermatomyositis
Clinical History:73-year-old man who presented with inability to rise from a chair.Past medical history: arthritis, hypertension and hypercholesterolemia, and male…
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Clinical History:The patient is a 65-year-old woman with progressive proximal and generalized weakness, dysphasia, full-body pain, fasciculations and malaise.Medication: IVIG…
Vasculitis: Using Fluorescence Microscopy to Visualize Elastic Lamina
Clinical History:This 65-year-old patient presented with a two-month history of progressive proximal upper and lower extremity muscle weakness, and photosensitive…
Glom Goals: A Blueprint for Better Renal Biopsies
In this episode of Glom Goals, we spoke to Dr. Salil Parikh from the Methodist Le Bonheur Healthcare group in…
Glom Goals: Why Adequacy Matters
Renal pathologists Dr. Shree Sharma and Dr. Tiff Caza sit down with nephrologists Dr. Juan Carlos Velez, Dr. Bill Whittier,…
Collagen Pockets in Nerve Biopsy
Clinical History:This 40-year-old patient underwent sural nerve biopsy to evaluate for a painful mixed large fiber and small fiber axonal…
Denervated Neuromuscular Junctions
Clinical History:Muscle biopsy from this 40-year-old patient showed morphologic and enzyme histochemical features of denervation.What abnormality is seen in the…
Gallyas Stain: Plaques, Tangles, and Threads in Alzheimer’s Disease
Clinical History:Neuropathologic examination (brain autopsy) on this 65-year-old patient with a history of slowly progressive dementia demonstrated gross and microscopic…
Myopathic changes on Alkaline phosphatase
Clinical History:This 40-year-old patient presented with complaints of muscle weakness and myalgias of approximately 3-months duration. Laboratory studies showed elevated…
Ring Fibers
Which genetic test is required to establish the diagnosis in this 59-year-old with distal muscle weakness, mild myotonia, and persistently…