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Diagnose This (August 22, 2022)
This is a 3 month post-transplant kidney biopsy from a patient with ESRD due to polycystic kidney disease. She recently…
Diagnose This (January 10, 2022)
This is the H&E from the frozen tissue submitted for IF examined under fluorescent light. In a patient with anemia,…
Twitter Poll (December 23, 2020)
Answer: D The histologic features of a thrombotic microangiopathy (TMA) are non-specific as to etiology and include both acute and…
Unresolved Etiologies: When the Clinical Acumen Takes Place
Dr. Silva comments on several diagnostic dilemmas where the pathology pattern leads to a plethora of possibilities.
Art of Medicine: Thrombotic Microangiopathy
The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…
KDIGO Connections: SLE and TMA
Remember to think about TMA lesions in your patients with lupus!
Disease Week: Onco-Nephrology
Monday Onco-nephrology is a rapidly developing area of nephrology designed to help address and prevent kidney problems and the many…
Art of Medicine: Collapsing Glomerulopathy
The above painting shows a glomerulus with capillary tuft collapse, visceral epithelial cell hyperplasia, and numerous protein resorption droplets within…
VEGF Inhibitor
The patient is a 70-year-old white female who presents with 4 gm/24 hr proteinuria and a creatinine of 1.2 mg/dl.…
Twitter Poll (March 28, 2018)
ANSWER: D Some of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli…
Diagnose This! (January 29, 2018)
What is your diagnosis? Immunofluorescence is negative. …
Twitter Poll (January 11, 2018)
ANSWER D: Tubulopathy with isometric vacuolization, acute tubular injury, acute arteriolopathy and TMA can be seen in acute CNIT.
Malignant Hypertension
This renal biopsy shown here is from a 25-year-old male who presented with acute kidney injury in the setting of…
Pushing Glass (October 10, 2017)
The patient is a 50-year-old African-American female with a past medical history significant for ESRD secondary to lupus nephritis who…
Opana
The histologic features of thrombotic microangiopathy (TMA) associated with intravenous abuse of extended-release oxymorphone hydrochloride (Opana ER) are shown in…