Search & Filter All Posts



All Articles

(22 Results)
Thrombotic microangiopathy
Diagnose This!

Diagnose This (August 22, 2022)

This is a 3 month post-transplant kidney biopsy from a patient with ESRD due to polycystic kidney disease. She recently…

thrombotic microangiopathy
Diagnose This!

Diagnose This (January 10, 2022)

This is the H&E from the frozen tissue submitted for IF examined under fluorescent light. In a patient with anemia,…

anti-brush border antibody disease, ABBA, renal pathology, Twitter Poll, arkana labs
Twitter Poll

Twitter Poll (December 23, 2020)

Answer: D The histologic features of a thrombotic microangiopathy (TMA) are non-specific as to etiology and include both acute and…

Unresolved etiologies, Throwback Thursday, Dr. Fred Silva, Arkana Laboratories

Unresolved Etiologies: When the Clinical Acumen Takes Place

Dr. Silva comments on several diagnostic dilemmas where the pathology pattern leads to a plethora of possibilities.

Fred Silva, MD renal pathologist at arkana laboratories
By Dr. Fred Silva
Thrombotic Microangiopathy
Art of Medicine

Art of Medicine: Thrombotic Microangiopathy

The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…

KDIGO Connections

KDIGO Connections: SLE and TMA

Remember to think about TMA lesions in your patients with lupus!  

Disease Week, onco-nephrology, cancer, nephropathology
Disease Week

Disease Week: Onco-Nephrology

Monday Onco-nephrology is a rapidly developing area of nephrology designed to help address and prevent kidney problems and the many…

Collapsing Glomerulopathy
Art of Medicine

Art of Medicine: Collapsing Glomerulopathy

The above painting shows a glomerulus with capillary tuft collapse, visceral epithelial cell hyperplasia, and numerous protein resorption droplets within…

VEGF, VEGF inhibitor, arkana laboratories, renal pathology
Teaching Points

VEGF Inhibitor

The patient is a 70-year-old white female who presents with 4 gm/24 hr proteinuria and a creatinine of 1.2 mg/dl.…

Sickle Cell Nephropathy
Twitter Poll

Twitter Poll (March 28, 2018)

ANSWER: D Some of the histologic features observed in Sickle Cell Nephropathy that involve the glomerular compartment are: enlarged glomeruli…

By Vanessa Moreno, MD
Thrombotic Microangiopathy
Diagnose This!

Diagnose This! (January 29, 2018)

What is your diagnosis? Immunofluorescence is negative.   …

By L. Nich Cossey, MD
Twitter Poll

Twitter Poll (January 11, 2018)

ANSWER D: Tubulopathy with isometric vacuolization, acute tubular injury, acute arteriolopathy and TMA can be seen in acute CNIT.

By Vanessa Moreno, MD

Malignant Hypertension
Teaching Points

Malignant Hypertension

This renal biopsy shown here is from a 25-year-old male who presented with acute kidney injury in the setting of…

acute antibody-mediated rejection
Pushing Glass

Pushing Glass (October 10, 2017)

The patient is a 50-year-old African-American female with a past medical history significant for ESRD secondary to lupus nephritis who…

Opana Associated TTP-Like Illness
Teaching Points


The histologic features of thrombotic microangiopathy (TMA) associated with intravenous abuse of extended-release oxymorphone hydrochloride (Opana ER) are shown in…