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IgG4-related disease
Diagnose This!

Diagnose This (September 10, 2018)

What is your diagnosis? This biopsy shows a chronic, active tubulointerstitial nephritis with sharp demarcation between affected and non-affected tissue…

By L. Nich Cossey, MD
Acute Interstitial Nephritis
By L. Nich Cossey, MD
Interstitial Eosinophils
Teaching Points

Interstitial Eosinophils

Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN). However, interstitial eosinophils are not…


Eosinophil-Rich Inflammation in Diabetic Glomerulopathy
Teaching Points

Eosinophil-Rich Inflammation in Diabetic Glomerulopathy

These photomicrographs are from a patient with diabetic nephropathy as evidenced by the Kimmelstiel-Wilson nodules in the glomerulus present on…

IgG4-Positive Plasma Cells
Teaching Points

IgG4

Renal parenchyma with florid interstitial fibrosis with thick bands of sclerosis expanding the interstitium and pushing the tubules apart on…