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IgG4-related disease
Diagnose This!

Diagnose This (September 10, 2018)

What is your diagnosis?This biopsy shows a chronic, active tubulointerstitial nephritis with sharp demarcation between affected and non-affected tissue and…

By L. Nich Cossey, MD
Acute Interstitial Nephritis
Diagnose This!

Diagnose This! (May 14, 2018)

What is your diagnosis?   ​   ​ ​   ​   ​ ​   ​   ​   ​  …

By L. Nich Cossey, MD
Interstitial Eosinophils
Teaching Points

Interstitial Eosinophils

Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).  However, interstitial eosinophils are not…


Eosinophil-Rich Inflammation in Diabetic Glomerulopathy
Teaching Points

Eosinophil-Rich Inflammation in Diabetic Glomerulopathy

These photomicrographs are from a patient with diabetic nephropathy as evidenced by the Kimmelstiel-Wilson nodules in the glomerulus present on…

IgG4-Positive Plasma Cells
Teaching Points

IgG4

Renal parenchyma with florid interstitial fibrosis with thick bands of sclerosis expanding the interstitium and pushing the tubules apart on…