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Necrotizing Vasculitis
Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle…
LECT2
Photomicrographs show extensive interstitial and glomerular deposition of Congo red positive material that stains positive for LECT2. Despite being one…
Cryoglobulinemic Glomerulonephritis
Figure 1: PAS-stained section showing a glomerulus with a membranoproliferative pattern of glomerular injury characterized by mesangial matrix expansion and…
Diffuse and Nodular Glomerulosclerosis in Diabetic Glomerulopathy
Diffuse and nodular glomerulosclerosis is the classic appearance of diabetic glomerulopathy. Note the variability in mesangial areas in this one…
THSD7A
Granular capillary loop staining for thrombospondin type-1 domain-containing 7A (THSD7A). Our understanding of the pathogenesis of membranous glomerulopathy was transformed…
Pushing Glass (April 4, 2017)
The patient is a 30-year-old female who presents with nephrotic range proteinuria and a creatinine of 2.5. She has a…
Pushing Glass (March 22, 2017)
A 71-year-old woman with a history of multiple myeloma, hypertension and vitamin D deficiency presented with decreased renal function. Investigations…
Diagnose This! (February 20, 2017)
The patient is a 42 y/o Southern Indian male who presents with longstanding, subnephrotic proteinuria, mild edema, and renal insufficiency.Pick…
