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Anti-GBM (Anti-Glomerular Basement Membrane)
Teaching Points

Anti-GBM

A 19-year-old Caucasian male patient presented with acute renal failure. Serum creatinine was 4.9 mg/dL and he had hematuria and…

Oxalate Nephropathy
Teaching Points

Oxalate Nephropathy

H&E stained section (Fig. 1) demonstrating acute tubular injury with frequent translucent intratubular crystalline deposits on a background of severe…

acute tubular injury with numerous pigmented myoglobin casts
Teaching Points

Myoglobin Casts

A 54-year-old man with a history of hypertension and hypercholesterolemia presented with complaints of generalized muscle stiffness and cola-colored urine.…


calcineurin inhibitor toxicity
Pushing Glass

Pushing Glass (April 18, 2017)

A 45 year-old man received renal transplantation for HCV-associated end stage renal disease. He is currently treated with Sofobuvir, Tacrolimus…

By Dao-Fu Dai, MD
Antibody-Mediated Rejection
Diagnose This!

Diagnose This! (April 17, 2017)

What is this stain and what does this finding mean in a transplant patient (Hint: Its not a vascular marker).…

By L. Nich Cossey, MD
Necrotizing Vasculitis
Teaching Points

Necrotizing Vasculitis

Necrotizing vasculitis as shown using fluorescence with DAPI-FITC-Texas Red excitation on an H&E stained section. Subtle and not so subtle…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

Cryoglobulinemic Glomerulonephritis
Teaching Points

Cryoglobulinemic Glomerulonephritis

Figure 1: PAS-stained section showing a glomerulus with a membranoproliferative pattern of glomerular injury characterized by mesangial matrix expansion and…

Light Chain Cast Nephropathy
Teaching Points

Light Chain Cast Nephropathy

Atypical fractured cast that is pale on PAS stain is suggestive of light chain cast nephropathy (LCCN). Immunofluorescence examination for…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD
Thrombotic Microangiopathy, renal biopsy, arkana laboratories, glomerulus
Diagnose This!

Diagnose This! (April 3, 2017)

What is your diagnosis?   …

By L. Nich Cossey, MD

Cryoglobulinemic glomerulonephritis
Pushing Glass

Pushing Glass (March 22, 2017)

A 71-year-old woman with a history of multiple myeloma, hypertension and vitamin D deficiency presented with decreased renal function. Investigations…

By Md Shahrier Amin, MD
Anti-Glomerular Basement Membrane Disease
Pushing Glass

Pushing Glass (March 14, 2017)

The patient is a 61-year-old female who presents with hematuria and a creatinine of 6.23 mg/dL (baseline creatinine of 1.17…

Anti-Brush Border Antibody Tubulointerstitial Nephritis
Diagnose This!

Diagnose This! (February 13, 2017)

Please pick the best answer. These images show characteristic findings of which of the following diseases: A) IgG4-Related Disease B)…

By L. Nich Cossey, MD