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Acute kidney injury, anti-centromere antibodies, ischemia, schistoctes, scleroderma renal crisis, thrombotic microangiopathy, scleroderma
Teaching Points

Scleroderma

The patient is a 32-year-old African American female who presents with hypertensive urgency, positive ANA, positive anti-RNA polymerase III antibody,…

Acute kidney injury, chryoglobulinemia, glomerulonephritis, hyaline thrombi, masked deposits, paraffin immunofluorescence, Cryoglobulinemic Glomerulonephritis
Teaching Points

Cryoglobulinemic Glomerulonephritis

The patient is a 60-year-old male who presents with proteinuria, hematuria, and a creatinine of 2.8 mg/dL. He was in…

VEGF, VEGF inhibitor, arkana laboratories, renal pathology
Teaching Points

VEGF Inhibitor

The patient is a 70-year-old white female who presents with 4 gm/24 hr proteinuria and a creatinine of 1.2 mg/dl.…


renal hemosiderosis, arkana laboratories, teaching point, renal pathology
Teaching Points

Hemosiderosis

An 80-year-old white male presents with a creatinine of 4.2 (baseline 1.1) on routine lab examination. His medical history is…

AL-Type Amyloidosis, teaching point, arkana laboratories, renal pathology, kidney biopsy
Teaching Points

AL Amyloidosis

A 70 year-old female presents with nephrotic range proteinuria and a creatinine of 1.2. She was in her normal level…

Lupus Nephritis, arkana laboratories, teaching point, nephropathology
Teaching Points

Lupus Nephritis (Class IV)

A 20-year-old female presents with hematuria, proteinuria, and a creatinine of 1.2 mg/dl. Serologies for ANA are positive. Complement levels…


Renal oxalosis, arkana laboratories, teaching point at arkana Laboratories, renal pathology
Teaching Points

Renal Oxalosis

A 25-year-old female presents to the hospital with malaise and a creatinine of 3.5. She reports that she was in…

Minimal Change Disease, teaching point, arkana laboratories, renal pathology
Teaching Points

Minimal Change Disease

A 70-year-old female presents with nephrotic range proteinuria.She had been in her regular state of health until 2 weeks ago…

Infection-Associated Glomerulonephritis
Teaching Points

Infection-Associated Glomerulonephritis

A 60-year-old male presents with a painful left hip, hematuria, and a creatinine of 1.5 mg/dl. He was recently hospitalized…


IgA Dominant Infection-Associated Glomerulonephritis, renal pathology
Teaching Points

IgA Dominant Infection-Associated Glomerulonephritis

A 65-year-old male presents to the ER with a new onset rash and blood in his urine. The ER doc…

A Tale of Two Cores, cores, arkana laboratories, renal pathology
Teaching Points

A tale of two cores…

Core A and B were taken from the same patient during the same biopsy procedure. The red blood cells within…

Malakoplakia, renal pathology, arkana laboratories
Teaching Points

Where is the normal kidney tissue?

This kidney biopsy shows the histologic features characteristic of malakoplakia, which includes a dense, often obliterative, inflammatory infiltrate rich in…


The image captures the transition of an arteriole (arteriole transition)
Teaching Points

Arteriole Transition

The image captures the transition of an arteriole (arteriole transition) as it loses its internal elastic lamina (black arrow). Note…

IgA nephropathy in renal biopsy from Arkana Laboratories
Teaching Points

IgA nephropathy with something extra…

The biopsy is from a 61-year-old man with a history of intermittent microscopic hematuria for many years who presents with…

Infection-Associated Glomerulonephritis in renal biopsy
Teaching Points

Infection-Associated Glomerulonephritis

This biopsy is taken from a 39-year-old woman who presents with abdominal pain, ascites, and lower extremity edema. Her serum…