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Antibody-Mediated Rejection
Teaching Points

Antibody-Mediated Rejection

This biopsy was performed on a 37-year-old female with a history of type 1 diabetes mellitus, status post second deceased…

renal vein thrombosis
Teaching Points

Renal Vein Obstruction

This biopsy is from a 60-year-old female, status post renal transplant 5 days prior, who was found to have mechanical…

intimal arteritis
By L. Nich Cossey, MD

acute antibody-mediated rejection
Pushing Glass

Pushing Glass (October 10, 2017)

The patient is a 50-year-old African-American female with a past medical history significant for ESRD secondary to lupus nephritis who…

Adenovirus
Diagnose This!

Diagnose This! (October 2, 2017)

What is your diagnosis in this renal allograft biopsy?   …

By L. Nich Cossey, MD
chronic transplant arteriopathy
Teaching Points

Chronic Transplant Arteriopathy

This image shows an arterial cross-section with features of chronic transplant arteriopathy (a.k.a. sclerosing transplant vasculopathy and chronic allograft vasculopathy).…


Glomerulitis
Teaching Points

Glomerulitis

This image (Jones silver stain) shows prominent glomerulitis in an allograft kidney biopsy, characterized in this case by increased mononuclear…

Chronic Antibody Mediated Rejection
Diagnose This!

Diagnose This (August 21, 2017)

What is this finding and what does it mean?   …

By L. Nich Cossey, MD
BK virus in renal biopsy at Arkana Laboratories
Teaching Points

BK Nephritis

This biopsy is from a patient with ESRD due to polycystic kidney disease. He is s/p deceased donor renal transplant…

Patrick D. Walker, MD renal pathologist at arkana laboratories
By Patrick D. Walker, MD

(CMV) Cytomegalovirus
Teaching Points

(CMV) Cytomegalovirus

The biopsy from this adult kidney transplant recipient shows features of cytomegalovirus (CMV) infection, including prominent enlargement (cytomegalo-) of tubular…

positive adenovirus IHC stain
Diagnose This!

Diagnose This! (June 19, 2017 )

Whats your diagnosis in this renal transplant?   …

By L. Nich Cossey, MD
Renal Vein Obstruction
Teaching Points

Renal Vein Obstruction

This biopsy is from a 60-year-old female, status post renal transplant 5 days prior, who was found to have mechanical…


Intimal Arteritis
Teaching Points

Intimal Arteritis

The image in Figure 1 shows mild intimal arteritis in an allograft biopsy from a patient who had undergone a…

BK nephritis
Pushing Glass

Pushing Glass (May 30, 2017)

A 62-year-old Asian male with a past medical history significant for ESRD secondary to hypertension S/P renal transplant (9 months…

calcineurin inhibitor toxicity
Pushing Glass

Pushing Glass (April 18, 2017)

A 45 year-old man received renal transplantation for HCV-associated end stage renal disease. He is currently treated with Sofobuvir, Tacrolimus…

By Dao-Fu Dai, MD