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Antiphospholipid Antibody Syndrome
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for…
Twitter Poll (April 18, 2018)
ANSWER: C Shiga toxin-producing E. coli is one of the most common pathogens involved in foodborne disease outbreak linked to…
Diagnose This! (January 29, 2018)
What is your diagnosis? Immunofluorescence is negative. …
Twitter Poll (January 11, 2018)
ANSWER D: Tubulopathy with isometric vacuolization, acute tubular injury, acute arteriolopathy and TMA can be seen in acute CNIT.
Malignant Hypertension
This renal biopsy shown here is from a 25-year-old male who presented with acute kidney injury in the setting of…
Pushing Glass (October 10, 2017)
The patient is a 50-year-old African-American female with a past medical history significant for ESRD secondary to lupus nephritis who…
Opana
The histologic features of thrombotic microangiopathy (TMA) associated with intravenous abuse of extended-release oxymorphone hydrochloride (Opana ER) are shown in…
Thrombotic Microangiopathy
This biopsy is from a person in their 40s, who presented with accelerated hypertension and blood pressure of 240/180 mm/Hg.…
Diagnose This! (August 14, 2017)
An immunofluorescence panel for IgA, IgG, IgM, C3, C1q, kappa and lambda was negative. What is your diagnosis? …
Vascular Endothelial Growth Factor
The biopsy shown here is from a seven-year-old female with nephrotic syndrome. Her serum Cr was increased to 0.9 mg/dl…
Thrombotic Microangiopathy
The image (trichrome stain) shows the characteristic arteriolar lesion of acute thrombotic microangiopathy. Note the prominent mucoid intimal edema and…
Postpartum HUS
Postpartum hemolytic uremic syndrome This 22-year-old Caucasian female presented with acute renal failure and proteinuria five days after delivering her…
