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Acute Tubular Injury With Pigmented Casts
This biopsy is a 54-year-old female without significant past medical history, who presented with acute kidney injury. The serum creatinine…
Minimal Change Disease and Acute Kidney Injury
This 81-year-old male with past medical history of hypertension and coronary artery disease presents with acute kidney injury (Cr =…
Lead Toxicity
The arrow in this image points to a cluster of tubular epithelial cells whose nuclei contain eosinophilic intranuclear inclusions characteristic…
Tenofovir
A wide variety of prescription and over the counter drugs may cause toxic injury to the renal tubular epithelium. Given…
IgAN and Acute Tubular Injury with Legionella
Acute kidney injury in the setting of Legionella pneumonia. This biopsy is a middle-aged person with Legionella pneumonia who developed…
2,8-Dihydroxyadenuria
Adenine phosphoribosyltransferase (APRT) deficiency results from an autosomal recessive enzyme defect of purine metabolism and leads to 2,8-dihydroxyadenine (2,8-DHA) crystalline…
Acute Pyelonephritis
The renal biopsy image shows features characteristic of acute pyelonephritis. There is a neutrophil-rich interstitial inflammatory infiltrate and evidence of…
BK Nephritis
This biopsy is from a patient with ESRD due to polycystic kidney disease. He is s/p deceased donor renal transplant…
Warfarin
Patients with warfarin-related nephropathy present with an acute rise in serum Cr after becoming supratherapeutic on warfarin therapy (INR>3). The…
Hemoglobin
The H&E photomicrographs show acute tubular injury with eosinophilic beaded casts (arrow). Immunohistochemical stains were strongly positive hemoglobin in the…
Oxalate Nephropathy
This biopsy is from a patient with metabolic acidosis, a CPK of 8000 mg/dl a creatinine of 22 mg/dl on…
Oxalate Nephropathy
H&E stained section (Fig. 1) demonstrating acute tubular injury with frequent translucent intratubular crystalline deposits on a background of severe…
Myoglobin Casts
A 54-year-old man with a history of hypertension and hypercholesterolemia presented with complaints of generalized muscle stiffness and cola-colored urine.…
Pushing Glass (April 18, 2017)
A 45 year-old man received renal transplantation for HCV-associated end stage renal disease. He is currently treated with Sofobuvir, Tacrolimus…
