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C3 Glomerulonephritis, Arkana Laboratories, Disease Week, renal disease, kidney pathology
Disease Week

Disease Week: C3 Glomerulonephritis

Monday Rediscovery of Complement Mesangial C3 deposition only within the glomerulus has been reported since 1980. Only recognized recently as…

Membranous Nephropathy, renal diseases, kidney biopsy, arkana laboratories
Teaching Points

Membranous Nephropathy After Transplantation

The biopsy shows a recurrent membranous nephropathy within a transplant. Figure 1 shows “spikes” and “holes.” Figure 2 shows mild…

Lysozyme Nephropathy, art of medicine
Art of Medicine

Art of Medicine: Lysozyme Nephropathy

The painting above shows acute tubular injury with numerous intracytoplasmic inclusions within proximal tubular epithelium, which can be seen in…


diffuse foot process effacement, Minimal change disease, Nephrotic syndrome, Podocytopathy, Arkana Laboratories
Diagnose This!

Diagnose This (April 22, 2019)

What is this finding and what diagnoses does it imply?   …

By L. Nich Cossey, MD
Collapsing Glomerulopathy, APOL1, arkana laboratories, kidney disease, renal pathology
Twitter Poll

Twitter Poll (April 17, 2019)

ANSWER: D Collapsing glomerulopathy has been associated with certain infectious disease including HIV, Hepatitis C, HTLV-1, parvovirus B19, cytomegalovirus, tuberculosis,…

By Vanessa Moreno, MD
AL-type Amyloidosis, arkana laboratories, diagnose this, renal path, kidney path, nephropath, chronic kidney disease
Diagnose This!

Diagnose This (April 1, 2019)

What is your diagnosis?     …

By L. Nich Cossey, MD

Nephrotic Syndrome, Arkana Laboratories, renal pathology, kidney injury
By L. Nich Cossey, MD
AL-Type Amyloidosis, teaching point, arkana laboratories, renal pathology, kidney biopsy
Teaching Points

AL Amyloidosis

A 70 year-old female presents with nephrotic range proteinuria and a creatinine of 1.2. She was in her normal level…

Art of Medicine

Art of Medicine: Light Chain Proximal Tubulopathy

The painting above shows light chain proximal tubulopathy with crystals, which is one type of a monoclonal gammopathy of renal…


Disease Week, Membranous glomerulopathy, disease week, arkana laboratories
Disease Week

Disease Week: Membranous Glomerulopathy

Monday History of MG Timeline of major discoveries in membranous glomerulopathy.   Heymann nephritis was unique as a model of…

apolipoprotein IV (AAPOAIV) in the kidney
Twitter Poll

Twitter Poll (January 30, 2019)

ANSWER: B The medulla is the only compartment affected by AAPOAIV amyloidosis, sometimes with large amounts of amyloid. Glomeruli and…

By Vanessa Moreno, MD
Fabry & Myelinosomes, Art of Medicine
Art of Medicine

Art of Medicine: Fabry

The image above shows myelinosomes, also known as zebra bodies for their appearance on tangential sectioning. Myelinosomes are seen in…


KDIGO Connections

KDIGO Connections: PLA2R-Positive Membranous Glomerulonephritis

KDIGO has some recommendations for anti-PLA2R testing in the research setting, but do you follow anti-PLA2R levels in your patients…

CLL/SLL Patients, arkana laboratories,
Twitter Poll

Twitter Poll (January 23, 2019)

ANSWER: A Although glomerular disease in patients with CLL/SLL is less common, the most frequent patterns of glomerular injury seen…

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Minimal Change Disease, teaching point, arkana laboratories, renal pathology
Teaching Points

Minimal Change Disease

A 70-year-old female presents with nephrotic range proteinuria.She had been in her regular state of health until 2 weeks ago…