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(159 Results)Disease Week: C3 Glomerulonephritis
Monday Rediscovery of Complement Mesangial C3 deposition only within the glomerulus has been reported since 1980. Only recognized recently as…
Membranous Nephropathy After Transplantation
The biopsy shows a recurrent membranous nephropathy within a transplant. Figure 1 shows “spikes” and “holes.” Figure 2 shows mild…
Art of Medicine: Lysozyme Nephropathy
The painting above shows acute tubular injury with numerous intracytoplasmic inclusions within proximal tubular epithelium, which can be seen in…
Diagnose This (April 22, 2019)
What is this finding and what diagnoses does it imply? …
Twitter Poll (April 17, 2019)
ANSWER: D Collapsing glomerulopathy has been associated with certain infectious disease including HIV, Hepatitis C, HTLV-1, parvovirus B19, cytomegalovirus, tuberculosis,…
AL Amyloidosis
A 70 year-old female presents with nephrotic range proteinuria and a creatinine of 1.2. She was in her normal level…
Art of Medicine: Light Chain Proximal Tubulopathy
The painting above shows light chain proximal tubulopathy with crystals, which is one type of a monoclonal gammopathy of renal…
Disease Week: Membranous Glomerulopathy
Monday History of MG Timeline of major discoveries in membranous glomerulopathy. Heymann nephritis was unique as a model of…
Twitter Poll (January 30, 2019)
ANSWER: B The medulla is the only compartment affected by AAPOAIV amyloidosis, sometimes with large amounts of amyloid. Glomeruli and…
Art of Medicine: Fabry
The image above shows myelinosomes, also known as zebra bodies for their appearance on tangential sectioning. Myelinosomes are seen in…
KDIGO Connections: PLA2R-Positive Membranous Glomerulonephritis
KDIGO has some recommendations for anti-PLA2R testing in the research setting, but do you follow anti-PLA2R levels in your patients…
Twitter Poll (January 23, 2019)
ANSWER: A Although glomerular disease in patients with CLL/SLL is less common, the most frequent patterns of glomerular injury seen…
Minimal Change Disease
A 70-year-old female presents with nephrotic range proteinuria.She had been in her regular state of health until 2 weeks ago…