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Focal and Segmental Glomerulosclerosis
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Diagnose This (February 7, 2022)

In a patient with subnephrotic proteinuria, negative immunofluorescence, and segmental foot process effacement, what is your diagnosis? …

anti-brush border antibody disease
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Diagnose This (January 31, 2022)

This is the IgG immunofluorescence from the biopsy of a 75-year-old female with AKI requiring dialysis. What is your diagnosis?…

ANCA-associated vasculitis
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Diagnose This (January 24, 2022)

In a patient with RPGN and this morphological finding on biopsy, what is the most likely diagnosis? …


collapsing glomerulopathy in APOL1
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Diagnose This (January 17, 2022)

This is the albumin immunofluorescence stain from a biopsy from a patient with recent COVID pneumonia and nephrotic syndrome. What…

thrombotic microangiopathy
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Diagnose This (January 10, 2022)

This is the H&E from the frozen tissue submitted for IF examined under fluorescent light. In a patient with anemia,…

Diagnose This!

Diagnose This (January 3, 2022)

In a renal allograft biopsy with this finding, what is your diagnosis? …


IgG, Anti-TBM Interstitial Nephritis
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Diagnose This (December 20, 2021)

This is the biopsy of a 68-year-old female with a history of bone marrow transplant and AKI. What is your…

diabetes
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Diagnose This (December 6, 2021)

Which underlying systemic disease does this patient most likely have? …

fibrillary glomerulopathy (FGN)
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Diagnose This (November 22, 2021)

In a non-diabetic patient, with positive IgG, kappa and lambda staining by immunofluorescence, what is your diagnosis? …


Amyloidosis, AA amyloid, IV drug, proteinuria
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Diagnose This (August 24, 2021)

This is the biopsy of a 32yo IV drug user who has nephrotic range proteinuria and MSSA bacteremia secondary to…

Amyloid Proximal Tubulopathy
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Diagnose This (August 2, 2021)

This biopsy is from a 61yo male with DM, CHF, CKD4, and an abnormal SPEP. UMOD IHC was negative. What…

sickled cell within a glomerular capillary
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Diagnose This (June 14, 2021)

What would be your diagnosis for these findings in a 30-year-old African American male with CKD stage III and proteinuria?…


intravascular large B-cell lymphoma (LBCL) in renal biopsy at Arkana Laboratories
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Diagnose This (May 31, 2021)

This is a CD20 immunohistochemical stain. Knowing that these cells are mostly within peritubular capillaries, what is your diagnosis? …

hronic active antibody-mediated rejection biopsy at arkana laboratories
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Diagnose This (May 25, 2021)

In an allograft biopsy, what would be your diagnosis for this combination of findings? …

juxtaglomerular apparatus hyperplasia in renal biopsy at Arkana Laboratories
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Diagnose This (May 10, 2021)

What is your diagnosis for this finding in a young patient with renal artery stenosis? …