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Arterioles, Venules, and Lymphatics
Clinical History This 50-year-old patient presented with right thigh pain. Their muscle biopsy showed mild denervation type changes. Several small…
Spinal Cord Lesion
Clinical History This 45-year-old patient presented with a 2-month history of right upper extremity pain. MRI demonstrated the presence of…
Squash Prep Astrocytic Neoplasm
Clinical History: This 65-year-old patient presented with new onset seizures. Their past medical history was significant for atrial fibrillation. MRI…
Patient with “Mechanic’s Hands”
Clinical History This 40-year-old patient presented with progressive proximal upper and lower extremity muscle weakness (difficulty ascending stairs and lifting…
Nerve Twig
Clinical history This 60-year-old patient presented with proximalmuscle weakness and pain of one-months duration. Laboratory studies showed elevated CPK (~12000).…
Mild Nonspecific Changes with Significant Genetic Finding
Clinical History This 30-year-old patient presented with complaints of severe exertional muscle stiffness and pain, and similar symptoms upon exposure…
Unilateral Calf Enlargement
Clinical History 61-year-old man who presented with several month history of right calf enlargement. Past medical history: TIA Relevant medications:…
27 Weeks Gestation
Clinical History This patient is a newborn male born at 27 wks, 2 days gestation. 25y.o. mother is G1P1 w/…
Weakness and Atrophy
Clinical History This 75-year-old man with amyotrophic lateral sclerosis (ALS) for 5 years has a past medical history of gout…
Skull Base Cyst
Clinical History This 35-year-old woman presented with dysphagia and dysphonia. MRI showed a CSF filled, thin-walled cyst compressing medulla. Question…
Rapidly Enlarging Mass in NF1 Patient
Clinical History: This 25-year-old patient with a history of Neurofibromatosis type 1(NF1) was found to have a relatively rapidly enlarging…
T-tubular Network
Electron microscopy on a muscle biopsy with myopathic changes showed an incidental waffle-like structure within the sarcoplasm (see arrow). This…
Satellite Cell Division
Electron microscopy on a muscle biopsy with myopathic changes showed a satellite cell undergoing cellular division. Note the condensed chromosomes…
Segmental COX-Negative Fibers
Clinical History This 40-year-old female who presented with generalized muscle weakness, progressive ptosis and cognitive impairment. Question What of the…
Neuromyositis
Clinical History This 60-year-old patient presented with complaints of proximal greater than distal muscle weakness. Laboratory studies showed normal CPK…