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Pushing Glass (September 7, 2018)
The patient is a 75-year-old female who presents with proteinuria and a creatinine of 2.50. She has chronic lymphocytic leukemia,…
Twitter Post (August 30, 2018)
ANSWER: B Type II (mixed) cryoglobulinemia is characterized by immune-complexes containing a monoclonal Ig (usually IgM) that have an RF…
Differential Diagnosis of Kidney Injury in CLL/SLL Patients
There are many causes of decreased kidney function in patients with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), and a renal…
Diagnose This (August 27, 2018)
What is this finding and what is the likely etiology? …
Twitter Poll (August 22, 2018)
ANSWER: D Anti-GBM disease is a rare small vessel vasculitis that affects glomerular and pulmonary capillaries. The majority of patients…
Diagnose This (August 20, 2018)
What is your presumed diagnosis in the absence of immunofluorescence and electron microscopy? …
One little, two little, three little findings…
This biopsy came to us for evaluation of nephrotic syndrome. The patient is a Hispanic gentleman in his late 80s,…
Twitter Poll (August 15, 2018)
ANSWER: D TMA is a lesion with multiple etiologies including HUS, TTP, STEC- HUS, complement dysregulation (atypical HUS), malignant HTN,…
Twitter Poll (August 1, 2018)
ANSWER: A The criteria for acute T-cell mediated rejection Banff grade IA includes interstitial inflammation involving >25% of non-sclerotic cortical…
Renal Arterial Thromboemboli
Infective endocarditis can have numerous deleterious effects on the kidney. One such renal complication is the formation of arterial thromboemboli.…
Endocapillary Hypercellularity in Thrombotic Microangiopathy
This renal biopsy performed on a 14-year-old boy shows changes diagnostic of a thrombotic microangiopathy (TMA). These changes include frequent…
Twitter Poll (July 26, 2018)
ANSWER: C The patient has a Diffuse Lupus Nephritis, Class IV-S (A). Although biopsy shows focal and segmental proliferative glomerulonephritis…
Anti-VEGF Effect
This biopsy was taken from an older adult man with acute kidney injury and non-nephrotic range proteinuria. His medical history…
HIV-Related Kidney Disease: HIVAN
This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.…
Diagnose This (July 16, 2018)
What is your diagnosis in this native kidney biopsy? And for bonus points, what do you suspect is the underlying…