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Epidermal Nerve Fiber Density

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Arkana Laboratories now offers Epidermal Nerve Fiber Density (ENFD) Testing. ENFD testing is widely used by neurologists in the United States and Europe to evaluate for small fiber neuropathy.

Specimen Handling and Transport:

It is essential that skin biopsy is immediately-fixed in the provided fixative (Zamboni’s) for evaluation (see additional instructions below).

  1. Specimens Accepted:

    Transport of specimen needs to be the same day the biopsy is performed (i.e. reliable results are obtained when the specimen is not fixed for more than 24 hours).  Store the biopsy specimen(s) in the refrigerator until ready to ship with a cool pack in the supplied kit box. We accept skin biopsy specimens Monday through Friday. Please DO NOT transport specimens on Friday, Saturday or over holidays.

  2. Epidermal Nerve Fiber Density Kits

    Kits are provided to you at no charge. Each kit provides for proper collection, fixation, identification, and transport of muscle biopsies for the following:
    – instruction sheet
    – requisition sheet
    – 3.0 mm biopsy punch biopsy kit with scissors and forceps, sterile (x1)
    – specimen container (x1) containing Zamboni’s fixative (stable for 1 year at room temperature)
    – plastic specimen bag with absorbent material to transport specimen containers within