About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(511 Results)
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Central HIV-1 Tat Exposure Elevates Anxiety And Fear Conditioned Responses Of Male Mice Concurrent With Altered Mu-Opioid Receptor-Mediated G-Protein Activation And Β-Arrestin 2 Activity In The Forebrain
Co-exposure to opiates and HIV/HIV proteins results in enhanced CNS morphological and behavioral deficits in HIV(+) individuals and in animal…
Read on PubMed• February 2016
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Multisite Assessment Of NIA-AA Guidelines For The Neuropathologic Evaluation Of Alzheimer’s Disease
Neuropathologic assessment is the current “gold standard” for evaluating the Alzheimer’s disease (AD), but there is no consensus on the…
Read on PubMed• February 2016
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Cerebral Amyloid Angiopathy-Related Inflammation: A Potentially Reversible Cause Of Dementia With Characteristic Imaging Findings
Cerebral amyloid angiopathy with inflammation (CAA-I) is a less well-recognized clinically and radiologically distinct subtype of CAA.
Read on PubMed• February 2016
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5α-Reduced Progestogens Ameliorate Mood-Related Behavioral Pathology, Neurotoxicity, And Microgliosis Associated With Exposure To HIV-1 Tat
Human immunodeficiency virus (HIV) is associated with motor and mood disorders, likely influenced by reactive microgliosis and subsequent neural damage.…
Read on PubMed• January 2016
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A Novel Alzheimer Disease Locus Located Near The Gene Encoding Tau Protein
APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci.
Read on PubMed• January 2016
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Association Of Apol1 Genotype With Renal Histology Among Black Hiv-Positive Patients Undergoing Kidney Biopsy
Prior studies have shown that the APOL1 risk alleles are associated with a greater risk of HIV-associated nephropathy and FSGS…
Read on PubMed• December 2015
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Bk Polyoma Virus Infection And Renal Disease In Non-Renal Solid Organ Transplantation
BK virus (BKV) is a non-enveloped DNA virus of the polyomaviridae family that causes an interstitial nephritis in immunosuppressed patients.…
Read on PubMed• December 2015
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Association Of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals
Mutations in known causal Alzheimer disease (AD) genes account for only 1% to 3% of patients and almost all are…
Read on PubMed• November 2015
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Radiologic Evidence That Hypothalamic Gliosis Is Associated With Obesity And Insulin Resistance In Humans
To use quantitative magnetic resonance imaging (MRI) to test whether mediobasal hypothalamic (MBH) gliosis is associated with obesity and insulin…
Read on PubMed• November 2015
