diagnostic image of nerve and muscle biopsy sent to arkana laboratories

Who We Are

Arkana Laboratories is a center for esoteric pathology focused on one thing: improving care for patients.

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diagnostic image of a renal biopsy sent to arkana laboratories showing glomerulus

Our Services

Featured Publications

Clinicopathologic Features of Antibrush Border Antibody Disease Clinicopathologic Features of Antibrush Border…

By Joel D. Murphy, Tiffany N. Caza, Clarissa A. Cassol, Aaron Storey, Josephine M Ambruzs, Christie Boils, Patrick D. Walker, Shree Sharma, Nidia Messias, Randolph…

February 2024

Antibrush Border Antibody Disease (ABBA), is a rare condition affecting the kidneys, particularly in older individuals,…

Antibrush Border Antibody Disease (ABBA), is a rare condition affecting the kidneys, particularly in older individuals, leading to kidney failure. By studying patients and their responses to treatment, it contributes to our understanding of how ABBA…

Read on kirereports.org

Development and Validation of a Multiclass Model Defining Molecular Archetypes of… Development and Validation of a Multiclass Model…

By Hao Zhang, Randy S. Haun, Francois Collin, Clarissa Cassol, Johnathan O.H. Napier, Jon Wilson, Samar Hassen, Kerime Ararat, Christie Boils, Nidia Messias, Tiffany N.…

December 2023

Gene expression profiling from formalin-fixed paraffin-embedded (FFPE) renal allograft biopsies is a promising approach…

Gene expression profiling from formalin-fixed paraffin-embedded (FFPE) renal allograft biopsies is a promising approach for feasibly providing a molecular diagnosis of rejection. However, large-scale studies evaluating the performance of models…

Read on Laboratory Investigation

The Banff 2022 Kidney Meeting Work Plan: Data-driven refinement of the Banff… The Banff 2022 Kidney Meeting Work Plan:…

By Roufosse C, Naesens M, Haas M, Lefaucheur C, Mannon RB, Afrouzian M, Alachkar N, Aubert O, Bagnasco SM, Batal I, Bellamy COC, Broecker V, Budde K, Clahsen-Van Groningen…

November 2023

The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada, from September 19 to 23, 2022, as a…

The XVIth Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada, from September 19 to 23, 2022, as a joint meeting with the Canadian Society of Transplantation. In addition to a key focus on the impact of microvascular…

Read on amjtransplant.org

Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…

By Palmer MB, Royal V, Jennette JC, Smith AR, Liu Q, Ambruzs JM, Andeen NK, D'Agati VD, Fogo AB, Gaut J, Gbadegesin RA, Greenbaum LA, Hou J, Helmuth ME, Lafayette RA,…

October 2023

Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…

Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…

Read on Karger.com

Shiga toxin targets the podocyte causing hemolytic uremic syndrome through… Shiga toxin targets the podocyte causing hemolytic…

By Bowen EE, Hurcombe JA, Barrington F, Keir LS, Farmer LK, Wherlock MD, Ortiz-Sandoval CG, Bruno V, Bohorquez-Hernandez A, Diatlov D, Rostam-Shirazi N, Wells S, Stewart M,…

October 2023

  • The podocyte is likely the reason Shiga toxin targets the…

    • The podocyte is likely the reason Shiga toxin targets the glomerulus in STEC-HU
    • Podocyte-to-glomerular endothelial cell…

Read on cell.com

Mayo Clinic Consensus Report on Membranous Nephropathy: Proposal for a Novel… Mayo Clinic Consensus Report on Membranous…

By Sethi S, Beck LH Jr., Glassock RJ, Haas M, De Vriese AS, Caza TN, Hoxha E, Lambeau G, Tomas NM, Madden B, Debiec H, D'Agati VD, Alexander MP, Amer H, Appel GB, Barbour…

October 2023

Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with…

Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune complexes along the subepithelial region of glomerular basement membranes. The past 20 years have brought…

Read on Mayo Clinic

Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…

By Kouri AM, Caza TN, Beck LH Jr., Misurac JM, Evans MD, Phillips CL, Eadon MT, Larsen CP, Andreoli SP, Bu L, Rheault MN, Khalid M

August 2023

Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…

Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…

Read on kirereports.org
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Education

It’s not just a commitment to advancing our field. We love what we do. Whether you are a resident evaluating career fields, or a clinician who wants to see more from our point of view, we invite you to explore our opportunities for learning below:

View all educational resources

Featured Educational Resources

Renal Pathology Quizzes

The renal pathology quizzes are designed for nephrology fellows to help prepare for the boards and understand renal pathology.

View All Quizzes

Renal Pathology Fellowship

The Arkana renal pathology fellowship is a one-year program designed to train a well-rounded academic renal pathologist.

Learn More & Apply

Renal Rotation

With so much to do, many residents are forced to abbreviate their anatomic pathology training and gain little or no exposure to some of the most interesting subspecialties in pathology.

Learn More & Apply
diagnostic image of nerve biopsy sent to arkana laboratories

From the Blog

Necrotic myofibers, Rhabdomyolysis
Neuro Notes

Rhabdomyolysis

Clinical history This 20-year-old patient was found in a prolonged seizure state (status epilepticus of unknown duration). CPK levels at…

Jon Wilson, MD neuropathologist at arkana laboratories
By Jon Wilson, MD
Patient Resources

Focal Segmental Glomerulosclerosis (FSGS)

What is focal segmental glomerulosclerosis (FSGS)? Focal segmental glomerulosclerosis (commonly abbreviated asFSGS) is a kidney disease. It is one of…

Christie Boils, MD renal pathologist at arkana laboratories
By Christie Boils, MD
Kidneys for Kids abstract illustration
Patient Resources

Kidneys for Kids

What are the kidneys and what do they do? Your kidneys are organs shaped like beans (think kidney beans) and…

By Stephen Bonsib, M.D., M.S.
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