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Muscle Pain
Clinical History The patient is a 54-year-old man with lower extremity pain and edema, weakness and fever following a respiratory…
Collidescope Episode 4 | A Collision Case with IgA and IgG4
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Granulomatous Myositis
Clinical History The patient is a 59-year-old woman with progressive weakness x 3 years. Past medical history includes COPD improved…
Neuropathy Associated with Amyloid
Clinical History: This 66-year old patient presented with clinical features of mononeuropathy. Sural nerve biopsy showed features of a chronic…
Myophosphorylase Deficiency
Clinical History This 25-year-old patient presented with episodes of fatigue, myalgias and muscle weakness following even low-level exertion. These symptoms…
Collidescope Episode 3 | MN, CG, and Immune Complex Deposits within the Tubular Basement Membranes
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Collidescope Episode 2 | A Collision Case with Minimal Change Disease and Anti-brush Border Antibody Disease
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Brain Mass
Clinical History The 40-year-old immunocompromised patient was found to have a frontal lobe mass. What is your diagnosis? Correct Answer:…
Incidental Finding
Clinical History: This 50-year-old patient clinically presented with muscle weakness and elevated CPK. Myositis specific autoantibody panel was positive for…
Collidescope Ep. 1 | What Happens when IgA Nephropathy and Fibrillary Glomerulopathy Collide?
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Diagnose This 4/29/2024
What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…
Starch Granules
Clinical History: This 50-year-old patient underwent muscle biopsy to evaluate for muscle weakness. What is the material seen outside of…
Extrafusal and Intrafusal Fibers
Clinical History This 1-year-old patient underwent muscle biopsy to evaluate for hypotonia. What are the muscle fibers within the small…
Diagnose This 4/15/2024
Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…
Signet Ring Carcinoma
Clinical History This 50-year-old patient presented with muscle weakness and stiffness. They had recently been identified to have diffuse thickening…