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macrophagic myofasciitis
Neuro Notes

Macrophagic Myofasciitis

Clinical History This 60-year old patient presented with a several month history of progressive upper and lower extremity muscle weakness…

AIDP / Guillain-Barré syndrome
Neuro Notes

AIDP / Guillain-Barré syndrome

Clinical History This 50-year old patient with a past medical history of gastric sleeve operation presented with a two week…

McArdle disease
Neuro Notes

Leg Muscle Pain

Clinical History 35-year-old previously healthy woman presented with dark urine, severe pain & swelling in bilateral lower extremity 1 day…


Nemaline Myopathy
Neuro Notes

Nemaline Myopathy

Clinical History 45-year-old woman with mild, symmetric, slowly-progressive upper and lower extremity weakness beginning in childhood. Her past medical history…

Neuro Notes

Ring Fiber

Clinical History What is the finding in these electron micrographs and what is its clinical association? A. Ouroboros fiber …

Neuro Notes

Glioblastoma with Mesenchymal Metaplasia

Clinical History This 80-year old patient presented with new onset seizures. Brain MRI demonstrated a 4.6 x 3.4 x 3.0…


Neuro Notes

Fourth Ventricular Mass

Clinical History This 27-year-old patient presented with left leg numbness, low back pain and balance issues. MRI showed a 4.9…

Neuro Notes

Dural Mass

Clinical History This 50-year-old patient was found to have in incidental dural based mass. What is your diagnosis? Correct Answer…

Neuro Notes

Segmental Demyelination-Remyelination

What pathologic process is demonstrated by the low and higher magnification images of a teased nerve preparation? The image shows…


Mitochondrial myopathy
Neuro Notes

Longstanding Weakness

Clinical History The patient is a 72-year-old man with a 30 year history progressive, symmetric leg weakness and tingling. Past…

Active vasculitis with fibrinoid necrosis
Neuro Notes

Muscle Pain

Clinical History The patient is a 54-year-old man with lower extremity pain and edema, weakness and fever following a respiratory…

Collidescope

Collidescope Episode 4 | A Collision Case with IgA and IgG4

What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…


Granulomatous myopathy
Neuro Notes

Granulomatous Myositis

Clinical History The patient is a 59-year-old woman with progressive weakness x 3 years. Past medical history includes COPD improved…

Neuropathy Associated with Amyloid
Neuro Notes

Neuropathy Associated with Amyloid

Clinical History: This 66-year old patient presented with clinical features of mononeuropathy. Sural nerve biopsy showed features of a chronic…

Neuro Notes

Myophosphorylase Deficiency

Clinical History This 25-year-old patient presented with episodes of fatigue, myalgias and muscle weakness following even low-level exertion. These symptoms…