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Granulomatous myopathy
Neuro Notes

Granulomatous Myositis

Clinical History The patient is a 59-year-old woman with progressive weakness x 3 years. Past medical history includes COPD improved…

Neuropathy Associated with Amyloid
Neuro Notes

Neuropathy Associated with Amyloid

Clinical History: This 66-year old patient presented with clinical features of mononeuropathy. Sural nerve biopsy showed features of a chronic…

Neuro Notes

Myophosphorylase Deficiency

Clinical History This 25-year-old patient presented with episodes of fatigue, myalgias and muscle weakness following even low-level exertion. These symptoms…


Collidescope

Collidescope Episode 3 | MN, CG, and Immune Complex Deposits within the Tubular Basement Membranes

What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…

Collidescope

Collidescope Episode 2 | A Collision Case with Minimal Change Disease and Anti-brush Border Antibody Disease

What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…

Toxoplasma gondii
Neuro Notes

Brain Mass

Clinical History The 40-year-old immunocompromised patient was found to have a frontal lobe mass. What is your diagnosis? Correct Answer:…


Neuro Notes

Incidental Finding

Clinical History: This 50-year-old patient clinically presented with muscle weakness and elevated CPK. Myositis specific autoantibody panel was positive for…

Collidescope

Collidescope Ep. 1 | What Happens when IgA Nephropathy and Fibrillary Glomerulopathy Collide?

What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…

Diagnose This!

Diagnose This 4/29/2024

What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…


Neuro Notes

Starch Granules

Clinical History: This 50-year-old patient underwent muscle biopsy to evaluate for muscle weakness. What is the material seen outside of…

Neuro Notes

Extrafusal and Intrafusal Fibers

Clinical History This 1-year-old patient underwent muscle biopsy to evaluate for hypotonia. What are the muscle fibers within the small…

Diagnose This!

Diagnose This 4/15/2024

Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…


Neuro Notes

Signet Ring Carcinoma

Clinical History This 50-year-old patient presented with muscle weakness and stiffness. They had recently been identified to have diffuse thickening…

Neuro Notes

Oxidative Stain Pallor

Clinical History This 60-year-old patient presented with progressive symmetrical subacute onset proximal muscle weakness involving their lower and upper extremities.…

Diagnose This!

Diagnose This 4/1/2024

What is this finding and what is the significance in the transplant setting?   The light microscopic image depicts an…