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Treated Pompe Disease
Clinical History:The patient is a young child a year prior to the current biopsy to have compound heterozygous GAA variants.…
Small Unmyelinated Axons
Clinical History:This 40-year-old patient presented with progressive neuropathic symptoms affecting their distal lower extremities and hands. A sural nerve biopsy…
Arkana Receives NIH Phase I SBIR Award to Advance Kidney Transplant Diagnostics
We’re excited to share that Arkana has received a $266,613 Phase I Small Business Innovation Research (SBIR) grant from the…
Lipid Storage Disorder
Clinical History:Demographics: 50-year-old womanChief complaint: Progressive generalized weakness for 6 weeks starting distally in hands and feet and progressed to…
Myofibrillar Myopathy / Distal Myopathy: Two Cases
Clinical History:Both of these patients were identified to have mutations in the FNLC gene, albeit in regions that affect different…
Hemosiderin Pigment
Clinical History:This 80-year-old patient presented with complaints of left lower leg muscle pain clinically suspicious for myositis. Their past medical…
Fasciitis With or Without Eosinophilia
Clinical History:This 40-year-old patient presented with progressive skin thickening of several months duration involving their arms and legs. Laboratory studies…
Perineuritis
Clinical History:This 60-year-old patient presented with clinical and electrophysiologic features of mononeuritis multiplex. Their past medical history was significant for…
Arkana Laboratories Named a 2026 Best Place to Work in Arkansas
We have been named one of the 2026 Best Places to Work in Arkansas. This recognition means a great deal…
Graft-Versus-Host Disease Myopathy
Clinical History:The patient is a 62-year-old woman with myalgia and symmetric proximal weakness.PMH: Myelodysplastic syndrome (MDS) Complicated by acute myelogenous…
Celebrating 25 Years: A Look Back at Arkana’s Anniversary Week
This month, Arkana Laboratories marked a significant milestone — 25 years of advancing diagnostic pathology and serving patients across the…
Iron Deposition – Vasculitic Neuropathy
Clinical History: CC: The patient is a 76-year-old woman progressive lower extremity then upper extremity anesthesia and dysesthesia, right then…
Myopathic Changes: Internalized Nuclei
Clinical History:This 60-year-old patient presented with bilateral proximal lower extremity muscle weakness of four years duration with some foot numbness.…
Regenerated Cluster
Clinical History:This 25-year-old patient presented with a one-year history of progressive bilateral upper and lower extremity muscle weakness and painful…
Axonopathy
Clinical History: The patient is a 72-year-old man. Clinical diagnosis of neuropathy. What cannot be seen on this electron micrograph…