The Kidneys and How They Work illustration
Patient Resources

The Kidneys and How They Work

Where are the kidneys and why do we need kidneys? The kidneys are a pair of bean-shaped organs, each about…

Systemic Lupus Erythematosus, SLE, lupus nephritis, arkana laboratories, disease week, renal pathology
Disease Week

NIH Lupus Nephritis Activity and Chronicity Indices

NIH Lupus Nephritis Activity and Chronicity Indices: A way to monitor response to treatment and disease progression. A semi-quantitative grading…

Subepithelial Humps, irregular subepithelial deposits
Teaching Points

Subepithelial Humps

The depicted electron micrograph shows numerous, large and irregular subepithelial deposits which protrude from the glomerular basement membrane towards the…

AA Amyloidosis, glomerular crescent
Renal Review

Case 2: A Crescentic Conundrum

The patient is a 75-year-old female with a history of hypertension who presents with acute kidney injury.  Her serum creatinine…

Plasma Cell Rich Interstitial Nephritis
Art of Medicine

Art of Medicine: Plasma Cell Rich Interstitial Nephritis

The above painting shows plasma cell rich interstitial inflammation with lymphocytic and plasma cell tubulitis, findings that can be seen…

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Popular Posts

Kidneys for Kids abstract illustration
Patient Resources

Kidneys for Kids

What are the kidneys and what do they do? Your kidneys are organs shaped like beans (think kidney beans) and…

"Pinholes" on Silver Stain
eyeSCANdy

“Pinholes” on Silver Stain

Todays eyeSCANdy image shows acellular scanning EM from a biopsy with membranous glomerulonephritis, stage I with numerous small shallow depressions…

Armanni Ebstein Lesion
Teaching Points

Armanni Ebstein Lesion

Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…


Diagnose This!

The biopsy shows glomerular capillary wall double contouring, segmental glomerular microaneurisms and hyalinosis. These findings are typical of anti-VEGF therapy-induced glomerular microangiopathy.
Diagnose This!

Diagnose This (October 10, 2022)

This is the biopsy of a 47-year-old female with cervical cancer, on anti-VEGF therapy, with proteinuria and normal renal function.…

Diagnose This!

Diagnose This (September 26, 2022)

This is the biopsy from a 73-year-old with AKI and normal bone marrow biopsy done for investigation of anemia and…

NPHP1-related nephronophthisis
Diagnose This!

Diagnose This (September 19, 2022)

In a 26-year-old obese Black female with no significant PMH and elevated creatinine, what is your top diagnosis?    …

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LDL Receptor-Related Protein 2