The Kidneys and How They Work
Where are the kidneys and why do we need them? The kidneys are a pair of bean-shaped organs, each about…
NIH Lupus Nephritis Activity and Chronicity Indices
NIH Lupus Nephritis Activity and Chronicity Indices: A way to monitor response to treatment and disease progression. A semi-quantitative grading…
Subepithelial Humps
The depicted electron micrograph shows numerous, large and irregular subepithelial deposits which protrude from the glomerular basement membrane towards…
Case 2: A Crescentic Conundrum
The patient is a 75-year-old female with a history of hypertension who presents with acute kidney injury. Her serum creatinine…
Art of Medicine: Plasma Cell Rich Interstitial Nephritis
The above painting shows plasma cell rich interstitial inflammation with lymphocytic and plasma cell tubulitis, findings that can be seen…
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Arkana is a learning, teaching, innovating practice with one unifying passion: to work toward research breakthroughs that make our services unnecessary.
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Kidneys for Kids
What are the kidneys and what do they do? Your kidneys are organs shaped like beans (think kidney beans) and…
“Pinholes” on Silver Stain
Todays eyeSCANdy image shows acellular scanning EM from a biopsy with membranous glomerulonephritis, stage I with numerous small shallow depressions…
Armanni-Ebstein Lesion
Armanni-Ebstein lesion, originally described by Luciano Armanni in 1872, is characterized by vacuolization and PAS-positive glycogen accumulation within the cytoplasm…
Diagnose This!
Diagnose This (October 10, 2022)
This is the biopsy of a 47-year-old female with cervical cancer, on anti-VEGF therapy, with proteinuria and normal renal function.…
Diagnose This (September 26, 2022)
This is the biopsy from a 73-year-old with AKI and normal bone marrow biopsy done for investigation of anemia and…
Diagnose This (September 19, 2022)
In a 26-year-old obese Black female with no significant PMH and elevated creatinine, what is your top diagnosis? …
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