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Neuro Notes

Myasthenia-Inflammatory Myopathy (MG-IM)

Clinical History:This 60-year-old patient presented with complaints of worsening hand weakness (particularly finger extensors). The weakness initially involved the right…

Life at Arkana

Celebrating Dr. Tiffany Caza’s Remarkable Contributions

We are thrilled to recognize Dr. Tiffany Caza, MD, PhD, for her outstanding impact in renal pathology and patient care.…

By Lex Woodruff
Neuro Notes

Denervation with Incidental Vascular Amyloid

Clinical History:This 76-year-old male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia,…


Neuro Notes

Toxic Vacuolar Myopathy Due to Hydroxychloroquine

Clinical History:This 50-year-old patient presented with a one year history of of persistent muscle weakness. They also had shortness of…

gomori trichrome of frozen tissue
Neuro Notes

Sporadic Late-Onset Nemaline Myopathy

Clinical History:The patient is a 69-year-old male who presented with complaints of proximal lower extremity muscle weakness and BMI of…

Figure 2: Oil-red O stained section of frozen muscle specimen
Neuro Notes

Lipid Storage Myopathy in 77-Year-Old Patient

Clinical History:The patient is a 77-year-old female with several months of progressive muscle weakness predominantly in her upper and lower…


image of Southern Tail Brewing decorated for Arkana's annual holiday party
Life at Arkana

2025 Holiday Party: A Very Arkana Christmas

On December 6, the Arkana team celebrated the holiday season at Southern Tail Brewing with friends and family for “A…

By Lex Woodruff
Toluidine blue stained image of vasculitic neuropathy
Neuro Notes

Vasculitic Neuropathy

Clinical History:65-year-old woman with generalized weakness and fatigue requiring a walker.Past medical history: anemia, major depressive disorder, MCI, arthritis, CTS,…

Gomori trichrome stained image of Anti-TIF1-γ in Dermatomyositis
Neuro Notes

Anti-TIF1-γ in Dermatomyositis

Clinical History:73-year-old man who presented with inability to rise from a chair.Past medical history: arthritis, hypertension and hypercholesterolemia, and male…


Gomori trichrome stained image of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Neuro Notes

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Clinical History:The patient is a 65-year-old woman with progressive proximal and generalized weakness, dysphasia, full-body pain, fasciculations and malaise.Medication: IVIG…

FFPE H&E immunofluorescence with FITC filter; image of vasculitis
Neuro Notes

Vasculitis: Using Fluorescence Microscopy to Visualize Elastic Lamina

Clinical History:This 65-year-old patient presented with a two-month history of progressive proximal upper and lower extremity muscle weakness, and photosensitive…

Glom Goals blue podcast cover art with image of a glomerulus
Podcast

Glom Goals: A Blueprint for Better Renal Biopsies

In this episode of Glom Goals, we spoke to Dr. Salil Parikh from the Methodist Le Bonheur Healthcare group in…

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By Dr. Shree Sharma

Podcast

Glom Goals: Why Adequacy Matters

Renal pathologists Dr. Shree Sharma and Dr. Tiff Caza sit down with nephrologists Dr. Juan Carlos Velez, Dr. Bill Whittier,…

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By Dr. Shree Sharma
collagen pockets in nerve biopsy case image
Neuro Notes

Collagen Pockets in Nerve Biopsy

Clinical History:This 40-year-old patient underwent sural nerve biopsy to evaluate for a painful mixed large fiber and small fiber axonal…

denervated neuromuscular junctions, lower magnification image or normal neuromuscular junction
Neuro Notes

Denervated Neuromuscular Junctions

Clinical History:Muscle biopsy from this 40-year-old patient showed morphologic and enzyme histochemical features of denervation.What abnormality is seen in the…