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Neuro Notes

Vascular Micromineralization

Clinical History This 40-year-old female patient presented with a three month of bilateral medial thigh pain and edema. Her past…

Diagnose This!

Diagnose This 1/29/2024

What stain would you order to clinch the diagnosis in this transplant patient with AKI?   A CMV stain is…

Diagnose This!

Diagnosis This 1/15/2024

What considerations should be included in your differential diagnosis given the provided histologic finding? The image of a Jones silver…


Longstanding weakness
Neuro Notes

Longstanding Weakness in an Adult

Clinical History 54-year-old woman. Family history negative for neuromuscular disease Longstanding (L>R) upper & lower extremity weakness Periodic falls &…

Ischemic myopathy
Neuro Notes

Patient with Painful Leg

Clinical History The 60-year-old patient was admitted for complaints of acute left lower extremity pain and weakness, and was found…

Lymphocytic hypophysitis
Neuro Notes

Pituitary Lesion

Clinical History This 35-year-old patient presented with headaches. MRI showed a sellar mass (diffuse enlargement of the pituitary gland) with…


Neuro Notes

Cauda equina mass

Clinical History This 40-year old patient with lumbar back pain. MRI demonstrated an intradural extramedullary mass at the level of…

Inclusion body myopathy , IBM,
Neuro Notes

11-year-old boy with falls

Clinical History 11-year-old boy Progressive weakness, Gower sign, falls 3 to 4 times a week, and leg pain PMH: ADHD,…

Dermatomyositis with treatment effect
Neuro Notes

Bulbar Weakness and Rash

Clinical History 68-year-old woman with dysphagia, dysarthria, facial muscle weakness and rash Past medical history breast cancer Medications hydroxychloroquine…


Degenerative axon/axonal-spheroid
Neuro Notes

Painful Ankle Mass

Clinical History 49-year-old woman Right-sided sural nerve mass Distal pain and numbness of the ankle What is the structure at…

Necrotic myofibers, Rhabdomyolysis
Neuro Notes

Rhabdomyolysis

Clinical history This 20-year-old patient was found in a prolonged seizure state (status epilepticus of unknown duration). CPK levels at…

Neuro Notes

Myofiber Injury

Clinical History The 50-year-old patient presented with proximal upper and lower extremity muscle weakness of several months duration. They also…


Neuro Notes

Patient with Ptosis and Weakness

Clinical history This 60-year-old patient presented with chronic ptosis and mild muscle weakness. CPK levels were within normal limits.  …

Neuro Notes

Arterioles, Venules, and Lymphatics

Clinical History This 50-year-old patient presented with right thigh pain. Their muscle biopsy showed mild denervation type changes. Several small…

Ependymoma
Neuro Notes

Spinal Cord Lesion

Clinical History This 45-year-old patient presented with a 2-month history of right upper extremity pain. MRI demonstrated the presence of…