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Collidescope Episode 2 | A Collision Case with Minimal Change Disease and Anti-brush Border Antibody Disease
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Brain Mass
Clinical History The 40-year-old immunocompromised patient was found to have a frontal lobe mass. What is your diagnosis? Correct Answer:…
Incidental Finding
Clinical History: This 50-year-old patient clinically presented with muscle weakness and elevated CPK. Myositis specific autoantibody panel was positive for…
Collidescope Ep. 1 | What Happens when IgA Nephropathy and Fibrillary Glomerulopathy Collide?
What happens when two diseases occur at the same time? Does one influence the other? How is kidney function affected?…
Diagnose This 4/29/2024
What would be your leading Dx and subtype based on the Congo red image above showing deposition predominately in the…
Starch Granules
Clinical History: This 50-year-old patient underwent muscle biopsy to evaluate for muscle weakness. What is the material seen outside of…
Extrafusal and Intrafusal Fibers
Clinical History This 1-year-old patient underwent muscle biopsy to evaluate for hypotonia. What are the muscle fibers within the small…
Diagnose This 4/15/2024
Based on the image provided, what would be your leading diagnosis with C3-dominant immune-complex deposition? The light microscopic image depicts…
Signet Ring Carcinoma
Clinical History This 50-year-old patient presented with muscle weakness and stiffness. They had recently been identified to have diffuse thickening…
Oxidative Stain Pallor
Clinical History This 60-year-old patient presented with progressive symmetrical subacute onset proximal muscle weakness involving their lower and upper extremities.…
Diagnose This 4/1/2024
What is this finding and what is the significance in the transplant setting? The light microscopic image depicts an…
Diagnose This 3/18/2024
What is at the top of your differential in a patient with a positive SPEP (IgG kappa) and the immunofluorescence…
Diagnose This 3/11/2024
What is your diagnosis in a patient with nephrotic syndrome? The electron photomicrograph demonstrates frequent subepithelial deposits along the glomerular…
Diagnose This 3/4/2024
The ultrastructural abnormalities present in the image are suspicious for what underlying disease? The electron photomicrograph demonstrates two abnormal…
Denervated Schwann cell
Clinical History This 50-year-old previously healthy patient presented with a several year history of progressive numbness, tingling and distal lower…