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Neuromuscular junction in 60-year-old patient
Clinical History:Muscle biopsy was performed on this 60-year-old patient to evaluate for subjective complaints of muscle weakness. Several small intramuscular…
Arkana at the Park
Our recent Arkana at the Park event at Burns Park was a refreshing break filled with sunshine, good food, and…
sIBM FFPE Thicks
Clinical History:This 55-year-old patient presented with complaints of a several year history of slowly progressive asymmetric upper and lower extremity…
Lipid storage myopathy in 50-year-old patient
Clinical History:The 50-year-old patient was admitted for shortness of breath and acute muscle weakness following a viral illness. Laboratory studies…
Cap myopathy
Clinical History:This 25-year-old patient presented with complaints of lower extremity muscle weakness. Their past medical history was significant for chronic…
Lymphocytes
Clinical History:Patient presented with progressive proximal weakness since August and severe x2 weeks.Past medical history: hyperthyroidism, hyperlipidemia, herpes simplex, hypertension.Medications:…
Pompe disease in teenage male
Clinical History:Teenage male with normal developmental milestones but difficulty playing sports or running.What is the diagnosis?Here are the diagnostic images…
Oxalate-induced nephropathy from ingestion of oxalic acid used miticide in beekeeping
Polarizable calcium oxalate microcrystals in a 16-year-old who ingested a small volume (<10 mL) of oxalic acid solution + grain…
MYCN-amplified spinal ependymoma
Clinical History:This 40-year-old patient has increasing back pain and lower extremity paraparesis. MRI of the cervical and lumbar spine with…
Calciphylaxis
Clinical History:This 50-year old patient presented complaints of upper and lower extremity proximal and distal muscle weakness. They also related…
Lab Week 2025: Mystery Under the Microscope
This year’s ASCP Medical Laboratory Professionals Week brought a thrilling twist to our celebration with “Mystery Under the Microscope,” a…
Split muscle fiber
Clinical HistoryThis 45-year-old patient underwent muscle biopsy to evaluate for muscle weakness. The biopsy showed denervation type changes (neurogenic atrophy).…
APOL1-Mediated Kidney Disease
What is APOL1-mediated kidney disease?APOL1-mediated kidney disease is a form of kidney diseases associated with changes that are known as…
Partially necrotic and regenerating myofibers
Clinical HistoryThe 21-year-old patient presented with skin rash and proximal upper and lower extremity weakness of several weeks duration. Laboratory…
Teenager with difficulty playing sports
Clinical HistoryTeenage male with normal developmental milestones but difficulty playing sports or running.What’s the diagnosis?Here are the diagnostic images for…