Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(452 Results)
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Ext1 And Ncam1-Associated Membranous Lupus Nephritis In A Cohort Of Patients Undergoing Repeat Kidney Biopsies
EXT1/2 and NCAM1 associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Read on PubMed• March 2022
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Cell Type-Specific Mechanistic Target Of Rapamycin-Dependent Distortion Of Autophagy Pathways In Lupus Nephritis
Pro-inflammatory immune system development, metabolomic defects, and deregulation of autophagy play interconnected roles in driving the pathogenesis of systemic lupus…
Read on PubMed• March 2022
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Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Read on Kidney International• March 2022
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Clinicopathologic features of non-lupus membranous nephropathy in a pediatric population
Membranous nephropathy is an uncommon cause of nephrotic syndrome in pediatrics.
Read on PubMed• March 2022
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Antibody-Suppressor Cxcr5 + Cd8 + T Cellular Therapy Ameliorates Antibody-Mediated Rejection Following Kidney Transplant In Ccr5 Ko Mice
CCR5 KO kidney transplant (KTx) recipients are extraordinarily high alloantibody producers and develop pathology that mimics human antibody-mediated rejection (AMR).
Read on PubMed• February 2022
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Llopregnanolone And Neurohiv: Potential Benefits Of Neuroendocrine Modulation In The Era Of Antiretroviral Therapy
Forty years into the HIV pandemic, approximately 50% of infected individuals still suffer from a constellation of neurological disorders collectively…
Read on PubMed• February 2022
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Lipoic Acid In Neural Epidermal Growth Factor-Like 1-Associated Membranous Nephropathy: More Than A Coincidence?
We found the study by Spainetal., Lipoic Acid Supplementation Associated With Neural Epidermal Growth Factor-Like 1 (NELL1)Associated Membranous Nephropathy, to…
Read on Kidney International• February 2022
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Association Of Antihypertensives That Stimulate Vs Inhibit Types 2 And 4 Angiotensin Ii Receptors With Cognitive Impairment
Use of antihypertensive medications that stimulate type 2 and 4 angiotensin II receptors, compared with those that do not stimulate…
Read on PubMed• January 2022
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Identification Of An Orally Bioavailable, Brain-Penetrant Compound With Selectivity For The Cannabinoid Type 2 Receptor
Modulation of the endocannabinoid system (ECS) is of great interest for its therapeutic relevance in several pathophysiological processes. The CB2…
Read on PubMed• January 2022
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Abi1-Based Expression Signature Predicts Breast Cancer Metastasis And Survival
Despite the current standard of care, breast cancer remains one of the leading causes of mortality in women worldwide, thus…
Read on PubMed• December 2021