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electron microscopy image of axonopathy
Neuro Notes

Axonopathy

Clinical History: The patient is a 72-year-old man. Clinical diagnosis of neuropathy. What cannot be seen on this electron micrograph…

Neuro Notes

Skeletal Muscle: Athletic Conditioning

Clinical History:This 17-year-old elite endurance athlete underwent muscle biopsy to evaluate for recent inability to perform at the level they…

Neuro Notes

Titin-Related Congenital Myopathy

Clinical History:The patient is a teenage male with past medical history end-stage renal dialysis and heart failure who presented with…


Neuro Notes

Toxoplasmosis: Encysted Spy of the CNS

Clinical History:A male patient in his 20s presents with recurrent fevers for 2 months progressing to 10 days of rapid…

Neuro Notes

Acute Upper and Lower Extremity Weakness

Clinical History: History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of…

Neuro Notes

MxA Positive Myopathy

Clinical History: History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of…


Neuro Notes

Vasculitis with Fibrinoid Necrosis

Clinical History: History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of…

Neuro Notes

68-Year-Old Man with Weakness

Clinical History:History: 68-year-old man with 1 week of bilateral proximal upper and lower extremity weakness and 1 month of facial,…

Neuro Notes

Needle Core Biopsy Muscle

Clinical History:This 50-year-old patient presented with progressively worsening muscle weakness of one month duration. Their past medical history was significant…


Neuro Notes

Myasthenia-Inflammatory Myopathy (MG-IM)

Clinical History:This 60-year-old patient presented with complaints of worsening hand weakness (particularly finger extensors). The weakness initially involved the right…

Neuro Notes

Denervation with Incidental Vascular Amyloid

Clinical History:This 76-year-old male presented with complaints of muscle pain. Their past medical history is significant for Sjogren’s syndrome, fibromyalgia,…

Neuro Notes

Toxic Vacuolar Myopathy Due to Hydroxychloroquine

Clinical History:This 50-year-old patient presented with a one year history of of persistent muscle weakness. They also had shortness of…


gomori trichrome of frozen tissue
Neuro Notes

Sporadic Late-Onset Nemaline Myopathy

Clinical History:The patient is a 69-year-old male who presented with complaints of proximal lower extremity muscle weakness and BMI of…

Figure 2: Oil-red O stained section of frozen muscle specimen
Neuro Notes

Lipid Storage Myopathy in 77-Year-Old Patient

Clinical History:The patient is a 77-year-old female with several months of progressive muscle weakness predominantly in her upper and lower…

Toluidine blue stained image of vasculitic neuropathy
Neuro Notes

Vasculitic Neuropathy

Clinical History:65-year-old woman with generalized weakness and fatigue requiring a walker.Past medical history: anemia, major depressive disorder, MCI, arthritis, CTS,…