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(72 Results)
h&E stain showing Toxoplasmosis
Neuro Notes

Toxoplasmosis

This 50-year old immunocompromised patient died after presenting with rapid cognitive decline and signs of brainstem dysfunction (cranial nerve deficits).…

Toxic Myopathy Due to Ingestion of Palytoxin, Low magnification image showing frequent scattered pale staining muscle fibers which have lost their nuclear staining for hematoxylin
Neuro Notes

Myalgias After Eating Fish

This 35-year-old previously healthy patient developed generalized myalgias, muscle weakness, and dark colored urine the day after eating cooked fish…

Neuro Notes

Intranuclear Cytoplasmic Pseudoinclusion

This 55 year-old patient presented with generalized muscle weakness and normal CPK.   Which of the following does the electron…


ADENOCARCINOMA, FETAL LUNG, METASTASIS, SUBNUCLEAR
Neuro Notes

Unusual Metastatic Carcinoma

This 70-year-old male patient was found to have a single 3.5 cm ring-enhancing left frontal lobe lesion with surrounding edema…

Succinic acid dehydrogenase (SDH) enzyme
Neuro Notes

Succinic Acid Dehydrogenase

This 60 year-old patient presented with distal asymmetric muscle weakness and normal CPK.   Which of the following abnormalities is…

Thioflavin T stain showing fibrillary inclusions
Neuro Notes

Thioflavin T sIBM

This 55-year old patient presented with a two-year history of proximal lower extremity weakness, difficulty grasping objects and atrophy of…


Freezing Artifact
Neuro Notes

Suboptimal Snap Freezing

This 50-year-old patient presented with a two year history of bilateral upper extremity muscle weakness. They also complained of muscle…

Russell Bodies on Gomori Trichrome Stain
Neuro Notes

Polymyositis With Plasma Cells

This 50-year-old patients muscle biopsy showed morphologic changes of polymyositis. Their past medical history is significant for rheumatoid arthritis. What…

Microfascicles
Neuro Notes

Toluidine Blue Stained Thick Section

This 75-year-old patient presented with complaints of numbness, tingling and burning sensation involving his right lower extremity below the level…


These changes shown on toluidine blue-stained thick section represent partial crush and/or traction artifact
Neuro Notes

Toluidine Blue Stained Thick Section

This 57-year-old patient presented with a left foot drop of several weeks duration. Laboratory studies showed elevated ESR, and negative/normal…

axon, Myelin incisure, Schmidt-Lanterman Incisure, myelin sheath
Neuro Notes

Schmidt-Lanterman Incisure

This 60-year-old patient presented with complaints of fatigue, lower back pain, and slowly progressive bilateral foot drop. Laboratory studies showed…

Diabetic, Neuropathy In A Diabetic Patient
Neuro Notes

Neuropathy In A Diabetic Patient

This patient presented with a multiple-year history of progressively worsening numbness and tingling which began in their feet and progressed…


IDH-Wildtype Glioblastoma
Neuro Notes

Unusual Brain Neoplasm

This 60-year-old patient presented with acute onset unilateral stroke-type symptoms. Imaging studies (brain CT and MRI) identified a left 5.0…

Fetal Brain
Neuro Notes

Fetal Brain

This image shows the brain of a twenty-six-week-old stillborn baby. What anatomic landmark is marked by the arrow in figure…

Neuro Notes

Unexpected Neuropathy

This 45-year-old previously healthy patient presented with a 4-year history of progressive numbness and dysesthesias involving their hands and feet…