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Muscle Pain
Clinical History The patient is a 54-year-old man with lower extremity pain and edema, weakness and fever following a respiratory…
Granulomatous Myositis
Clinical History The patient is a 59-year-old woman with progressive weakness x 3 years. Past medical history includes COPD improved…
Neuropathy Associated with Amyloid
Clinical History: This 66-year old patient presented with clinical features of mononeuropathy. Sural nerve biopsy showed features of a chronic…
Myophosphorylase Deficiency
Clinical History This 25-year-old patient presented with episodes of fatigue, myalgias and muscle weakness following even low-level exertion. These symptoms…
Brain Mass
Clinical History The 40-year-old immunocompromised patient was found to have a frontal lobe mass. What is your diagnosis? Correct Answer:…
Incidental Finding
Clinical History: This 50-year-old patient clinically presented with muscle weakness and elevated CPK. Myositis specific autoantibody panel was positive for…
Starch Granules
Clinical History: This 50-year-old patient underwent muscle biopsy to evaluate for muscle weakness. What is the material seen outside of…
Extrafusal and Intrafusal Fibers
Clinical History This 1-year-old patient underwent muscle biopsy to evaluate for hypotonia. What are the muscle fibers within the small…
Signet Ring Carcinoma
Clinical History This 50-year-old patient presented with muscle weakness and stiffness. They had recently been identified to have diffuse thickening…
Oxidative Stain Pallor
Clinical History This 60-year-old patient presented with progressive symmetrical subacute onset proximal muscle weakness involving their lower and upper extremities.…
Denervated Schwann cell
Clinical History This 50-year-old previously healthy patient presented with a several year history of progressive numbness, tingling and distal lower…
Regenerated Clusters
Clinical History This 60-year-old diabetic patient presented with complaints of bilateral chronic numbness and tingling involving their legs in a…
Unusual Inflammatory Neuropathy
Clinical History: This 60-year-old patient presented with a history of chronic progressive paresthesias involving all four extremities. Electrodiagnostic studies showed…
Vascular Micromineralization
Clinical History This 40-year-old female patient presented with a three month of bilateral medial thigh pain and edema. Her past…
Longstanding Weakness in an Adult
Clinical History 54-year-old woman. Family history negative for neuromuscular disease Longstanding (L>R) upper & lower extremity weakness Periodic falls &…