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(102 Results)![Lupus Nephritis Class III/IV](https://www.arkanalabs.com/wp-content/uploads/tp01.04-432x288.jpg)
Twitter Poll (January 4, 2018)
ANSWER: D Endocapillary hypercellularity, crescents, karyorrhexis and wire loops are some of the glomerular lesions seen in lupus nephritis class…
![Immunotactoid Glomerulopathy](https://www.arkanalabs.com/wp-content/uploads/tp12.20-432x288.jpg)
Twitter Poll (December 20, 2017)
ANSWER: D Immunotactoid glomerulopathy presents with Congo red-negative microtubular deposits with electron-lucent lumens measuring >30 nm in diameter.
![Phospholipase A2 Receptor 1](https://www.arkanalabs.com/wp-content/uploads/tp12.14-432x288.jpg)
Twitter Poll (December 14, 2017)
ANSWER: C Phospholipase A2 receptor 1 (PLA2R1) is present in podocytes and proximal tubules and has been detected in ~70%…
![Levamisole/Cocaine DAV](https://www.arkanalabs.com/wp-content/uploads/tp12.6-1-432x288.jpg)
Twitter Poll (December 6, 2017)
ANSWER: A Dual positivity for MPO and PR3 antibodies is a strong clue for levamisole/cocaine DAV.
![HCV](https://www.arkanalabs.com/wp-content/uploads/tp11.30-432x288.jpg)
Twitter Poll (November 30, 2017)
ANSWER: D Patients with HCV can present with membranoproliferative GN, Cryoglobulinemic GN, membranous GN, fibrillary GN, immunotactoid glomerulopathy and IgA…
![polyomavirus nephritis](https://www.arkanalabs.com/wp-content/uploads/tp11.22-432x288.jpg)
Twitter Poll (November 22, 2017)
ANSWER: C Immunohistochemistry for SV40 large-T antigen can detect BK and JC virus. It helps to diagnose polyomavirus nephritis; but…
![Fabry Disease](https://www.arkanalabs.com/wp-content/uploads/tp11.15-432x288.jpg)
Twitter Poll (November 15, 2017)
ANSWER: B Fabry disease causes a genetically derived deficiency in alpha-galactosidase A enzyme and accumulation of globotriaosylceramide (GL3).
![Anti-GBM Glomerulonephritis](https://www.arkanalabs.com/wp-content/uploads/tp11.08-1-432x288.jpg)
Twitter Poll (November 8, 2017)
ANSWER: B The characteristic immunofluorescence staining on Anti-GBM Glomerulonephritis is strong and linear IgG along glomerular basement membranes.
![Hematuria](https://www.arkanalabs.com/wp-content/uploads/tp10.18-432x288.jpg)
Twitter Poll (October 18, 2017)
Answer B is the best answer. Hematuria, while possible, is an uncommon presenting symptom of membranous glomerulopathy.
![Collapsing glomerulopathy](https://www.arkanalabs.com/wp-content/uploads/tp10.04-1-432x288.jpg)
Twitter Poll (October 4, 2017)
Answer: D Collapsing glomerulopathy has been associated with infection (HIV, parvovirus B19), drugs (INFs, BPs, CNIs) and APOL1-associated collapsing glomerulopathymutation…
![Fraction of Glomeruli With Crescents](https://www.arkanalabs.com/wp-content/uploads/tp9.27-432x288.jpg)
Twitter Poll (September 27, 2017)
B-The fraction of glomeruli w/ crescents is the sole discriminator between classes II through V. This system predicts the clinical…
![Amyloid Fibril Deposits](https://www.arkanalabs.com/wp-content/uploads/tp9.12-432x288.jpg)
Twitter Poll (September 12, 2017)
Answer: C Amyloid fibrils typically measure 8-12 nm (answer C). The deposits seen in Immunotactoid glomerulopathy are composed by tubules…