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Archive: Arkana Voices

Arkana’s Service: What’s It Worth?

Arkana's service, Arkana Laboratories
Arkana's Service: What's It Worth? Arkana's service has changed over the years. Since I joined Arkana Laboratories in 2011, our company and my role have changed considerably. At the time I joined we were known as Nephropath and we were a fast-growing renal pathology service. Since my time here we have expanded into Neuropathology, Molecular Pathology, Clinical and Contract Research, as well as added a variety of testing modalities to support our pathology services. All that change even necessitated a name change to Arkana Laboratories, which we felt better reflected our current service offerings as well as those which we...

Clinical Trials: Why Are They Important?

Dr. Abner, Clinical Trials, Arkana Laboratories
At Arkana Laboratories we are actively engaged in a variety of research areas, including clinical trials in which we currently assist in a variety of on-going trials from numerous pharmaceutical companies.  My name is Clint Abner, and I manage clinical trials and contract research here at Arkana. Medical trials are essential to disease research for finding new medications, treatments, and even cures for disease.  They are designed to answer questions that lead to improved health and quality of life for patients.  They can show researchers what does and does not work in humans, and often generate data that cannot be...

Zebrafish: How Can They Help Us?

zebrafish, Arkana Laboratories research
Zebrafish: How Can They Help Us? I have enjoyed working with laboratory zebrafish since 2003.  Zebrafish have become a very well accepted model organism for human disease due to rapid breeding, fast development, transparent embryos, and conservation of 70% of human genes.  Several human diseases have been successfully modeled using zebrafish such as acute lymphoblastic leukemia, melanoma, and Duchenne muscular dystrophy. The majority of my time with these fish was spent in the Vanderbilt University system where I was involved in diverse research areas such as gastrulation, fetal alcohol syndrome, holoprosencephaly, Menkes Disease, and obesity. I discovered that I like...

APOL1: Why Is It Important?

APOL1 gene, Arkana Laboratories, renal pathology research
I have been working at Arkana Laboratories (formerly Nephropath) for close to seven years as the Molecular Diagnostics Laboratory Supervisor. One of my first projects here was to isolate DNA from formalin-fixed, paraffin-embedded tissue and get an assay set up to determine variants in the APOL1 gene. At that time, these variants were recently discovered and there was great excitement in the scientific community as to their role in kidney disease, especially in African Americans, which is the population with the highest frequency of these gene variants in America. Our project involved the role of these variants in collapsing glomerulopathy...