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Glomerular Capillary Loops with Advanced Membranous Glomerulonephritis

Advanced Membranous Glomerulonephritis, stage IV, renal pathology, Bonsib, eyescandy, arkana laboratories
Today’s eyeSCANdy image shows acellular scanning EM of glomerular capillary loops from a biopsy with advanced membranous glomerulonephritis stage IV with shallow depressions and larger "craters" representing a second layer of basement membrane response on top of completely bridged GBM spikes.   Image courtesy of Dr. Stephen Bonsib.