©2016 All Rights Reserved.
Arkana Laboratories is a registered trademark.
Privacy and Terms
The above painting shows podocytes with foot processes extending along the glomerular basement membrane of neighboring capillary loops. Effacement of podocyte foot processes occurs in primary podocytopathies, including minimal change disease (see electron photomicrograph below). Minimal change disease is the most common etiology of idiopathic nephrotic syndrome in children and is the third most common cause in adults, after focal segmental glomerulosclerosis and membranous glomerulopathy. A majority of cases are “primary”, require no additional workup, and are due to a circulating permeability factor. Several possible secondary causes have also been identified. Although these are rare, these should be considered in...