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Considering the clinical vignette from the prior week (elderly male with proximal muscle weakness). Staining the skeletal muscle biopsy with Hematoxylin and Eosin (H&E) in combination with frozen sections evaluated with Modified Gomori Trichrome (MGT) and oxidative stains can provide the neuropathologist with much information, including clues as to the ultrastructural abnormality of this myopathy. Electron microscopy was pursued. Using the images, what is the ultrastructural abnormality shown below in this skeletal muscle biopsy? Formalin-fixed paraffin-embedding (FFPE) tissue section of skeletal muscle with Tubular Aggregate Myopathy (TAM) demonstrating four nearby muscle fibers with round to ovoid eccentric and subsarcolemmal...