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Tuesday: Let's start with a poll. You have a 25-year-old female patient with a positive ANA and proteinuria. On a kidney biopsy, light microscopy looks fairly unremarkable - a little mesangial expansion and mildly prominent capillary loops. IF is also nearly unremarkable, but with 2+ C3 staining. On EM, you have this finding. What do you do next? Stain the biopsy with PLA2R Perform IgG subclasses Do paraffin immunofluorescence There has to be a mix-up - check with the lab Answer - Paraffin Immunofluorescence What do you expect to find by paraffin immunofluorescence? Strong C3 staining to confirm C3...