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Archive: March 2017

Arkanines: Peaches

Happy Friday! Meet Peaches. She is 10 years old and holds a certificate as a “Canine Good Citizen” and also a Rally Novice title. Peaches loves people, especially if they have a treat. This happy girl belongs to Ann, one of our transcriptionists.

Pushing Glass (March 22, 2017)

A 71-year-old woman with a history of multiple myeloma, hypertension and vitamin D deficiency presented with decreased renal function. Investigations show serum creatinine increased to 3.36 mg/dL. Serum albumin is 2.6 gm/dL. Twenty-four hour urinary protein is 2.8 gm/day. These images show characteristic findings of which of the following diseases: A) Thrombotic microangiopathy B) Cast nephropathy C) Light chain deposition disease D) Cryoglobulinemic glomerulonephritis E) Amyloidosis F) Fibrillary glomerulopathy Answer: D The images show intracapillary hyaline, thrombi which are weakly PAS-positive, and stain red on silver and trichrome stains. These showed positive staining only for IgG1 and kappa light chain....

The Beauty of Pathology

"Every day pathologists look at shapes and colors on slides. Aside from the very crucial diagnosis that this analysis delivers, it can also bring the artist out in a person, triggering a comparison of what they see through the microscope with a completely unrelated image or encouraging the picking up of a paintbrush." -Fedora Pavlou, The Beauty of Pathology Artwork by: Arkana Nephropathologist, Stephen Bonsib

Pushing Glass (March 14, 2017)

The patient is a 61-year-old female who presents with hematuria and a creatinine of 6.23 mg/dL (baseline creatinine of 1.17 one month ago). What is the most likely diagnosis? A. Pauci-Immune Crescentic Glomerulonephritis B. Anti-Glomerular Basement Membrane Disease C. Crescentic Fibrillary Glomerulonephritis. D. Lupus Nephritis E. Early Diabetic Glomerulopathy The answer is B: The biopsy shows linear glomerular basement membrane staining for IgG, kappa, and lambda and this staining pattern is diagnostic of anti-glomerular basement membrane disease. Anti-glomerular basement membrane disease has a bimodal distribution in the general population. Younger patients (in their 20s) usually present with both hemoptysis and...

Sweet 16

Happy Sweet Sixteen, Arkana Labs! On March 1, 2001, Dr. Walker opened this practice with one goal in mind: to improve patient care. It's only fitting that we all get cars on our Sweet Sixteen.