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Skeletal muscle biopsy demonstrating changes of critical illness myopathy. (Figure 1) Hematoxylin and eosin (H&E)-stained section prepared from snap frozen skeletal muscle shows atrophic muscle with a subset of atrophic pale staining type 2 muscle fibers (fiber typing stains not shown), and relatively rare scattered mild nonspecific myopathic changes are seen through the specimen. (Figure 2) Muscle fibers have a blue tinctorial quality change on staining with Modified Gomori Trichrome (MGT). (Figure 3) Ultrastructural examination by electron microscopy (EM) shows loss of the myosin thick filaments and preservation of thin filaments and Z-lines. Original Magnifications: A. Frozen H&E, 100x; B....