In a patient who is an IV drug user and IF showing C3 only staining, what is your diagnosis?
The image shows global endocapillary hypercellularity with numerous neutrophils (exudative glomerulonephritis). The patient was found to have tricuspid valve endocarditis. Given the presence of C3-only deposits, paraffin immunofluorescence was performed to rule out “masked” deposits and was negative. The findings are consistent with infection-related glomerulonephritis.
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