Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(483 Results)
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Immunoglobulin-Negative DNAJB9-Associated Fibrillary Glomerulonephritis: A Report of 9 Cases
Fibrillary glomerulonephritis (FGN) was previously defined by glomerular deposition of haphazardly oriented fibrils that stain with antisera to immunoglobulins but…
Read on PubMed• March 2021
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Kidney Biopsy Findings In Patients With COVID-19, Kidney Injury, And Proteinuria
Acute tubular injury (AKI) develops in up to 37% of hospitalized patients with COVID-19 and its pathophysiology has not been…
Read on PubMed• March 2021
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Masson Trichrome And Sulfated Alcian Blue Stains Distinguish Light Chain Deposition Disease From Amyloidosis In The Lung
Light chain deposition disease, characterized by nonamyloidogenic deposits of immunoglobulin light chains, is rare in the lung and possibly underdiagnosed…
Read on PubMed• March 2021
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Membranous Nephropathy In A Patient With Coronavirus Disease 2019 (Covid-19): A Case Report
Though respiratory, immune, and coagulation systems are major targets of coronavirus disease 2019 (COVID-19), kidney dysfunction, presenting with acute kidney…
Read on PubMed• February 2021
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An Efficient Synthetic Route To L-γ-Methyleneglutamine And Its Amide Derivatives, And Their Selective Anticancer Activity
In cancer cells, glutaminolysis is the primary source of biosynthetic precursors, fueling the TCA cycle with glutamine-derived α-ketoglutarate. The enhanced…
Read on PubMed• February 2021
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Development And Evaluation Of Deep Learning-Based Segmentation Of Histologic Structures In The Kidney Cortex With Multiple Histologic Stains
The application of deep learning for automated segmentation (delineation of boundaries) of histologic primitives (structures) from whole slide images can…
Read on PubMed• January 2021
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Recurrence of Atrial Myxoma in Pregnancy: Successful Intrapartum Management and Postpartum Resection
Cardiac myxoma in pregnant women is extremely rare; with only 50 cases reported in the literature. Management warrants close consideration…
Read on Fortune Journals• January 2021
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Characteristics Of Patients With Coexisting Dnajb9-Associated Fibrillary Glomerulonephritis And Iga Nephropathy
Coexistence of fibrillary glomerulonephritis (FGN) and immunoglobulin A (IgA) nephropathy (IgAN) in the same kidney biopsy (FGN-IgAN) is rare, and…
Read on PubMed• December 2020
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Diffuse “Background” Monoclonal Light Chain Staining On Kidney Biopsies In The Absence Of Electron-Dense Deposits – Putting It Into Perspective: A Retrospective Cohort Study
Pathologic diagnosis of monoclonal gammopathy (MIg)-associated kidney disease requires specific morphologic and immunofluorescence (IF) findings with deposits on electron microscopy.
Read on PubMed• December 2020
