The mechanisms leading to extracellular matrix (ECM) replacement of areas of glomerular capillaries in histologic variants of FSGS are unknown.

Since the discovery of the causative agent for the novel severe acute respiratory syndrome (SARS)–like pneumonia syndrome pandemic that started…

Anti–brush border antibody disease (ABBAD) is a rare autoimmune disease associated with acute kidney injury and tubulointerstitial damage.

At least one-third of HIV-1-afflicted individuals experience peripheral neuropathy. Although the underlying mechanisms are not known, they may involve neurotoxic…

Immune checkpoint blockade has emerged as a highly effective treatment for patients with metastatic melanoma and cutaneous squamous cell carcinoma.

Collapsing glomerulopathy is an aggressive form of focal segmental glomerulosclerosis with diverse causes.

Common variable immunodeficiency (CVID) is one of the most common primary immunodeficiency syndromes, affecting one in 25,000–50,000 people.

The kidney’s role in filtration of blood and production of urine occurs via a combination of size and charge filtration…

The identification and proper characterization of pathologic renal intratubular casts can be an arduous task, especially since they often admixed…

Differential diagnosis of primary IgA nephropathy (IgAN) and IgA-dominant infection-related glomerulonephritis, particularly Staphylococcus infection−associated glomerulonephritis (SAGN), on a kidney biopsy…