Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.

All Publications
(478 Results)
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Persistent Increase In Mitochondrial Superoxide Mediates Cisplatin-Induced Chronic Kidney Disease
Severe and recurrent cisplatin-induced acute kidney injury (AKI) as part of standard cancer therapy is a known risk factor for…
Read on PubMed• January 2019
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Progressive loss of brain volume in children with sickle cell anemia and silent cerebral infarct: A report from the silent cerebral infarct transfusion trial
Silent cerebral infarcts (SCIs) in children with sickle cell anemia (SCA) are associated with increased risk of overt stroke,1new SCI,1poor…
Read on Wiley Online LibraryProgressive loss of brain volume in children with sickle cell anemia and silent cerebral infarct: A report from the silent cerebral infarct transfusion trial •
• December 2018
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Sex-Specific Genetic Predictors Of Alzheimer’s Disease Biomarkers
Cerebrospinal fluid (CSF) levels of amyloid- 42 (A42) and tau have been evaluated as endophenotypes in Alzheimer’s disease (AD) genetic…
Read on PubMed• December 2018
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Acute Renal Failure In A Patient With Pr3-Anca And Monoclonal Immunoglobulin Deposition Disease: Case Report
Acute renal failure developing over a short period of time with evidence of glomerular disease by urine sediment microscopy characterizes…
Read on PubMed• December 2018
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Anca-Associated Necrotizing Glomerulonephritis Overlapping With Mesangial Proliferative Lupus Nephritis Refractory To Plasmapheresis, Steroid Pulse Therapy, And A Combination Of Mycophenolate Mofetil And Rituximab
Necrotizing glomerulonephritis (GN) associated with antineutrophil cytoplasmic antibody (ANCA) has been increasingly recognized in the context of class III or…
Read on PubMed• November 2018
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Renal Manifestations Of Inflammatory Bowel Disease
The most common findings on renal biopsy of IBD patients are IgA nephropathy and tubulointerstitial nephritis.
Read on PubMed• November 2018
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Fluorescence In Situ Hybridization For The Diagnosis Of Nphp1 Deletion-Related Nephronophthisis On Renal Biopsy
Nephronophthisis is an autosomal recessive tubulointerstitial nephropathy that is a leading genetic etiology of end-stage renal disease in children and…
Read on PubMed• November 2018
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Methimazole-Induced Pauci-Immune Glomerulonephritis And Anti-Phospholipid Syndrome: An Important Association To Be Aware Of
While methimazole (MMI) is the first line treatment for hyperthyroidism, this medication is not devoid of adverse effects.
Read on PubMed• October 2018
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A Molecular Signature For Delayed Graft Function
Chronic kidney disease and associated comorbidities (diabetes, cardiovascular diseases) manifest with an accelerated ageing phenotype, leading ultimately to organ failure…
Read on PubMed• October 2018
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Genetically Elevated High-Density Lipoprotein Cholesterol Through The Cholesteryl Ester Transfer Protein Gene Does Not Associate With Risk Of Alzheimer’s Disease
There is conflicting evidence whether high-density lipoprotein cholesterol (HDL-C) is a risk factor for Alzheimer’s disease (AD) and dementia. Genetic…
Read on PubMed• September 2018
