Featured Publications
Multiplexed Detection of Membranous Nephropathy Antigens by Multi-Reaction… Multiplexed Detection of Membranous Nephropathy…
Membranous nephropathy (MN) is a kidney disease where the body's immune system mistakenly attacks proteins in the…
Membranous nephropathy (MN) is a kidney disease where the body's immune system mistakenly attacks proteins in the kidney's filtration barrier. Those target proteins are called antigens. Researchers have now identified over 30 different antigens that…
Framework for Apolipoprotein 1-Mediated Kidney Disease Classification Framework for Apolipoprotein 1-Mediated Kidney…
Our team at Arkana recently published updated guidance on how to report APOL1 genetic test results for kidney disease…
Our team at Arkana recently published updated guidance on how to report APOL1 genetic test results for kidney disease risk. Here's what you need to know: APOL1 is a gene variant found much more commonly in Black Americans, and carrying two copies…
Pulmonary-renal Syndrome Caused by an Overlap Systemic Lupus… Pulmonary-renal Syndrome Caused by an Overlap…
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 continues to be a global public health…
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 continues to be a global public health issue. Kidney disease is common, mainly presenting as acute kidney injury. Glomerular diseases have been reported in COVID-19. We…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(47 Results)
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Glomerular diseases post-hematopoietic stem cell transplantation: pathologic spectrum and plausible mechanisms
Haematopoietic stem cell transplantation (HSCT) can be a life-saving, curative treatment for patients with hematologic malignancies and hematologic disorders, with…
Read on Oxford Academic• February 2023
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Serologic Studies in Membranous Nephropathy: Novel Strategies and Strengthened Associations
Serologic studies have transformed clinical practice for patients with phospholipase A2 receptor (PLA2R)-positive membranous nephropathy (MN) by enabling noninvasive therapeutic…
Read on Kidney 360• February 2023
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Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-based proteomics. However, antigenic targets of disease are unknown for…
Read on Kidney International• January 2023
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Renal Prognosis of COVID-19 Associated Nephropathy
COVID-19 associated nephropathy (COVAN) is the most common cause of acute kidney injury (AKI) in Black patients with SARS-CoV-2 infection…
Read on KIReports• December 2022
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Traditional Indigenous Medicines Are An Etiologic Consideration For NELL1-positive Membranous Nephropathy
Traditional indigenous medicines (TIM) are founded on ancient historical practice. These medications are obtained over the counter, vary in composition,…
Read on PubMed• September 2022
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The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy
Membranous nephropathy (MN) is an immune kidney disease characterized by glomerular subepithelial immune complexes (ICs) containing antigen, IgG, and products…
Read on PubMed• July 2022
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What Can Mercury Teach Us About Membranous Nephropathy and Minimal Change Disease?
From clinical associations of environmental exposure beginning with the story of cationic bovine serum in pediatric membranous nephropathy (MN) more…
Read on PubMed• June 2022
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Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Read on Kidney International• March 2022
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Lipoic Acid In Neural Epidermal Growth Factor-Like 1-Associated Membranous Nephropathy: More Than A Coincidence?
We found the study by Spain et al., “Lipoic Acid Supplementation Associated With Neural Epidermal Growth Factor-Like 1 (NELL1)–Associated Membranous Nephropathy,” to…
Read on Kidney International• February 2022
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How Times Have Changed! A Cornucopia Of Antigens For Membranous Nephropathy
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the majority of primary (idiopathic) cases of membranous…
Read on PubMed• November 2021
