Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(45 Results)
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Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry
Multiple autoantigens have been identified in membranous nephropathy (MN) by tissue-based proteomics. However, antigenic targets of disease are unknown for…
Read on Kidney International• January 2023
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Renal Prognosis of COVID-19 Associated Nephropathy
COVID-19 associated nephropathy (COVAN) is the most common cause of acute kidney injury (AKI) in Black patients with SARS-CoV-2 infection…
Read on KIReports• December 2022
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Traditional Indigenous Medicines Are An Etiologic Consideration For NELL1-positive Membranous Nephropathy
Traditional indigenous medicines (TIM) are founded on ancient historical practice. These medications are obtained over the counter, vary in composition,…
Read on PubMed• September 2022
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The Alternative Pathway Is Necessary and Sufficient for Complement Activation by Anti-THSD7A Autoantibodies, Which Are Predominantly IgG4 in Membranous Nephropathy
Membranous nephropathy (MN) is an immune kidney disease characterized by glomerular subepithelial immune complexes (ICs) containing antigen, IgG, and products…
Read on PubMed• July 2022
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What Can Mercury Teach Us About Membranous Nephropathy and Minimal Change Disease?
From clinical associations of environmental exposure beginning with the story of cationic bovine serum in pediatric membranous nephropathy (MN) more…
Read on PubMed• June 2022
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Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Read on Kidney International• March 2022
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Lipoic Acid In Neural Epidermal Growth Factor-Like 1-Associated Membranous Nephropathy: More Than A Coincidence?
We found the study by Spain et al., “Lipoic Acid Supplementation Associated With Neural Epidermal Growth Factor-Like 1 (NELL1)–Associated Membranous Nephropathy,” to…
Read on Kidney International• February 2022
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How Times Have Changed! A Cornucopia Of Antigens For Membranous Nephropathy
The identification of the major target antigen phospholipase A2 receptor (PLA2R) in the majority of primary (idiopathic) cases of membranous…
Read on PubMed• November 2021
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Glomerular Disease In Temporal Association To SARS-CoV-2 Vaccination: A Series of 29 Cases
Immune responses to vaccination are a known trigger for a new onset of glomerular disease or disease flare in susceptible…
Read on PubMed• August 2021
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A Multi-Center Retrospective Cohort Study Defines The Spectrum Of Kidney Pathology In Coronavirus 2019 Disease (Covid-19)
Kidney failure is common in patients with Coronavirus Disease-19 (COVID-19), resulting in increased morbidity and mortality.
Read on PubMed• August 2021
