Featured Publications
Multiplexed Detection of Membranous Nephropathy Antigens by Multi-Reaction… Multiplexed Detection of Membranous Nephropathy…
Membranous nephropathy (MN) is a kidney disease where the body's immune system mistakenly attacks proteins in the…
Membranous nephropathy (MN) is a kidney disease where the body's immune system mistakenly attacks proteins in the kidney's filtration barrier. Those target proteins are called antigens. Researchers have now identified over 30 different antigens that…
Framework for Apolipoprotein 1-Mediated Kidney Disease Classification Framework for Apolipoprotein 1-Mediated Kidney…
Our team at Arkana recently published updated guidance on how to report APOL1 genetic test results for kidney disease…
Our team at Arkana recently published updated guidance on how to report APOL1 genetic test results for kidney disease risk. Here's what you need to know: APOL1 is a gene variant found much more commonly in Black Americans, and carrying two copies…
Pulmonary-renal Syndrome Caused by an Overlap Systemic Lupus… Pulmonary-renal Syndrome Caused by an Overlap…
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 continues to be a global public health…
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 continues to be a global public health issue. Kidney disease is common, mainly presenting as acute kidney injury. Glomerular diseases have been reported in COVID-19. We…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(47 Results)
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The Utility of Myeloperoxidase Immunostaining to Characterize Immune Deposits in Patients With Crescentic Glomerulonephritis
This study looked at MPO staining in a kidney disease called crescentic glomerulonephritis (GN), which is usually linked to a…
Read on Kidney International• March 2025
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Clinicopathologic Features of Kidney Disease in Patients With Cystic Fibrosis
Extrapulmonary complications of cystic fibrosis (CF) occur in nearly all adults living with the disease and renal manifestations are no…
Read on NCBI• July 2024
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Clinicopathologic Features of Antibrush Border Antibody Disease
Antibrush Border Antibody Disease (ABBA), is a rare condition affecting the kidneys, particularly in older individuals, leading to kidney failure.…
Read on kirereports.org• February 2024
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Development and Validation of a Multiclass Model Defining Molecular Archetypes of Kidney Transplant Rejection: A Large Cohort Study of the Banff Human Organ Transplant Gene Expression Panel
Gene expression profiling from formalin-fixed paraffin-embedded (FFPE) renal allograft biopsies is a promising approach for feasibly providing a molecular diagnosis…
Read on Laboratory Investigation• December 2023
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Mayo Clinic Consensus Report on Membranous Nephropathy: Proposal for a Novel Classification
Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune…
Read on Mayo Clinic• October 2023
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Clinical and Histopathologic Characteristics of Pediatric Patients With Primary Membranous Nephropathy
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In…
Read on kirereports.org• August 2023
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The Antigenic Landscape of Pediatric Membranous Nephropathy
Membranous nephropathy (MN) is rare in children, comprising 3% of pediatric nephrotic syndrome.MN may be underrecognized in children because the…
Read on kirereports.org• July 2023
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Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use
Drugs are an important secondary cause of membranous nephropathy (MN) with the most common drugs associated with MN being nonsteroidal…
Read on Kidney International• April 2023
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COVID-19 Vaccination and New Onset Glomerular Disease: Results from the IRocGN2 International Registry
IgAN and MCD are the most common de novo glomerular diseases reported after COVID-19 vaccination, particularly after mRNA vaccination. Membranous…
Read on Kidney 360• March 2023
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False-positive anti-PLA2R ELISA testing in patients with diabetes mellitus
We identified 2 similar patients with biopsy-proven diabetic nephropathy with false-positive phospholipase A2 receptor (PLA2R) testing by enzyme-linked immunosorbent assay…
Read on Kidney International• February 2023
