Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(45 Results)
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Clinicopathologic Features of Antibrush Border Antibody Disease
Antibrush Border Antibody Disease (ABBA), is a rare condition affecting the kidneys, particularly in older individuals, leading to kidney failure.…
Read on kirereports.org• February 2024
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Development and Validation of a Multiclass Model Defining Molecular Archetypes of Kidney Transplant Rejection: A Large Cohort Study of the Banff Human Organ Transplant Gene Expression Panel
Gene expression profiling from formalin-fixed paraffin-embedded (FFPE) renal allograft biopsies is a promising approach for feasibly providing a molecular diagnosis…
Read on Laboratory Investigation• December 2023
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Mayo Clinic Consensus Report on Membranous Nephropathy: Proposal for a Novel Classification
Membranous nephropathy (MN) is a pattern of injury caused by autoantibodies binding to specific target antigens, with accumulation of immune…
Read on Mayo Clinic• October 2023
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Clinical and Histopathologic Characteristics of Pediatric Patients With Primary Membranous Nephropathy
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In…
Read on kirereports.org• August 2023
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The Antigenic Landscape of Pediatric Membranous Nephropathy
Membranous nephropathy (MN) is rare in children, comprising 3% of pediatric nephrotic syndrome.MN may be underrecognized in children because the…
Read on kirereports.org• July 2023
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Proprotein convertase subtilisin/kexin type 6 (PCSK6) is a likely antigenic target in membranous nephropathy and nonsteroidal anti-inflammatory drug use
Drugs are an important secondary cause of membranous nephropathy (MN) with the most common drugs associated with MN being nonsteroidal…
Read on Kidney International• April 2023
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COVID-19 Vaccination and New Onset Glomerular Disease: Results from the IRocGN2 International Registry
IgAN and MCD are the most common de novo glomerular diseases reported after COVID-19 vaccination, particularly after mRNA vaccination. Membranous…
Read on Kidney 360• March 2023
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False-positive anti-PLA2R ELISA testing in patients with diabetes mellitus
We identified 2 similar patients with biopsy-proven diabetic nephropathy with false-positive phospholipase A2 receptor (PLA2R) testing by enzyme-linked immunosorbent assay…
Read on Kidney International• February 2023
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Glomerular diseases post-hematopoietic stem cell transplantation: pathologic spectrum and plausible mechanisms
Haematopoietic stem cell transplantation (HSCT) can be a life-saving, curative treatment for patients with hematologic malignancies and hematologic disorders, with…
Read on Oxford Academic• February 2023
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Serologic Studies in Membranous Nephropathy: Novel Strategies and Strengthened Associations
Serologic studies have transformed clinical practice for patients with phospholipase A2 receptor (PLA2R)-positive membranous nephropathy (MN) by enabling noninvasive therapeutic…
Read on Kidney 360• February 2023
