Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(45 Results)
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C-Abl Mediated Tyrosine Phosphorylation Of Aha1 Activates Its Co-Chaperone Function In Cancer Cells
The ability of Heat Shock Protein 90 (Hsp90) to hydrolyze ATP is essential for its chaperone function. The co-chaperone Aha1…
Read on PubMed• August 2015
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Targeting Hsp90 In Urothelial Carcinoma
Urothelial carcinoma, or transitional cell carcinoma, is the most common urologic malignancy that carries significant morbidity, mortality, recurrence risk and…
Read on PubMed• April 2015
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Endothelial Nitric Oxide Synthase Reduces Crescentic And Necrotic Glomerular Lesions, Reactive Oxygen Production, And Mcp1 Production In Murine Lupus Nephritis
Systemic lupus erythematosus, in both animal models and in humans, is characterized by autoantibody production followed by immune complex deposition…
Read on PubMed• May 2013
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Metabolic Regulation Of Organelle Homeostasis In Lupus T Cells
Abnormal T-cell signaling and activation are characteristic features in systemic lupus erythematosus (SLE). Lupus T cells are shifted toward an…
Read on PubMed• September 2012
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N-Acetylcysteine Reduces Disease Activity By Blocking Mammalian Target Of Rapamycin In T Cells From Systemic Lupus Erythematosus Patients: A Randomized, Double-Blind, Placebo-Controlled Trial
Systemic lupus erythematosus (SLE) patients exhibit T cell dysfunction, which can be regulated through mitochondrial transmembrane potential (Δψm) and mammalian…
Read on PubMed• September 2012
