Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(478 Results)
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Targeting Hsp90 In Urothelial Carcinoma
Urothelial carcinoma, or transitional cell carcinoma, is the most common urologic malignancy that carries significant morbidity, mortality, recurrence risk and…
Read on PubMed• April 2015
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Leukocyte Cell-Derived Chemotaxin 2-Associated Amyloidosis: A Recently Recognized Disease With Distinct Clinicopathologic Characteristics
Amyloidosis derived from leukocyte cell-derived chemotaxin 2 is a recently recognized form of amyloidosis, and it has already been established…
Read on PubMed• April 2015
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HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation
Cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol esters (CE) from atheroprotective high-density lipoproteins (HDL) to atherogenic low-density…
Read on PubMedHDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation •
• March 2015
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Monoclonal Igg1κ Anti-Glomerular Basement Membrane Disease: A Case Report
We report a case of anti-glomerular basement membrane (anti-GBM) nephritis with indolent course, monoclonal IgG1 (immunoglobulin G, subclass 1, …
Read on PubMed• February 2015
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Paraffin Immunofluorescence In The Renal Pathology Laboratory: More Than A Salvage Technique
Immunofluorescence studies on paraffin-embedded tissue after Pronase digestion (paraffin immunofluorescence) is used as a salvage technique in renal pathology, when…
Read on PubMed• February 2015
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Cerebral Cortical Aβ42 And PHF-Τ In 325 Consecutive Brain Autopsies Stratified By Diagnosis, Location, And APOE
We used a novel approach to molecular quantification in standard fixed and embedded tissue to measure amyloid 42 (A(42))…
Read on PubMed• February 2015
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Rarity Of The Alzheimer Disease-Protective APP A673T Variant In The United States
Recently, a rare variant in the amyloid precursor protein gene (APP) was described in a population from Iceland. This variant,…
Read on PubMed• February 2015
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Human Udp-Glucuronosyltransferases: Effects Of Altered Expression In Breast And Pancreatic Cancer Cell Lines
Increased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers.
Read on PubMed• January 2015
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Histopathologic Findings Associated With APOL1 Risk Variants In Chronic Kidney Disease
Compared with populations who lack recent African ancestry, African Americans have higher incidence rates of chronic kidney disease (CKD).Two coding…
Read on PubMed• January 2015
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Endothelin-1 Upregulation Mediates Aging-Related Cardiac Fibrosis
Endothelin-1 (ET-1) plays a major role in regulating myocardial fibrosis in several pathological conditions, such as hypertension and diabetes.
Read on PubMed• January 2015
