Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(478 Results)
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The Renal Biopsy
The first renal biopsy was carried out more than a century ago, but its widespread introduction into clinical use, beginning…
Read on Archives of Pathology & Laboratory Medicine• February 2009
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Free Radical Damage To Cerebral Cortex In Alzheimer’s Disease, Microvascular Brain Injury, And Smoking
Evidence supports a pathogenic role for free radical injury to brain in Alzheimer’s disease; however, clinical trial results are only…
Read on PubMed• February 2009
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Neuropathology-Based Risk Scoring For Dementia Diagnosis In The Elderly
Current neuropathologic consensus criteria for diagnosis of dementia yield a classification of processes that likely contributed to dementia in that…
Read on PubMed• January 2009
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Adjustment For Selection Bias In Observational Studies With Application To The Analysis Of Autopsy Data
The interpretation of neuropathological studies of dementia and Alzheimer’s disease is complicated by potential selection mechanisms that can drive whether…
Read on PubMed• January 2009
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Nociceptive And Anxiety-Like Behavior In Reproductively Competent And Reproductively Senescent Middle-Aged Rats
Changes in levels of estradiol and progesterone that occur with the transition to reproductive senescence may influence nociception or affect.
Read on PubMed• January 2009
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Alcohol Dose-Dependently Enhances 3α-Androstanediol Formation In Frontal Cortex of Male Rats Concomitant with Aggression
Alcohol (EtOH) can enhance aggression in people and animal models. These effects are more salient in males than in females.…
Read on Betham Open• January 2009
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Increasing 3alpha,5alpha-Thp Following Inhibition Of Neurosteroid Biosynthesis In The Ventral Tegmental Area Reinstates Anti-Anxiety, Social, And Sexual Behavior Of Naturally Receptive Rats
The progesterone metabolite and neurosteroid, 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP), has actions in the midbrain ventral tegmental area (VTA) to modulate lordosis, but…
Read on PubMed• September 2008
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Estrogen Is Necessary For 5α-Pregnan-3α-ol-20-One (3α,5α-THP) Infusion To The Ventral Tegmental Area To Facilitate Social And Sexual, But Neither Exploratory Nor Affective Behavior Of Ovariectomized Rats
The progesterone metabolite, 5-pregnan-3-ol-20-one (3,5-THP, allopregnanolone), acts in the ventral tegmental area (VTA) to facilitate exploratory, anti-anxiety, and socio-sexual behavior…
Read on PubMed• August 2008
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Biomarkers For Cognitive Impairment And Dementia In Elderly People
The threat of a looming pandemic of dementia in elderly people highlights the compelling need for the development and validation…
Read on PubMed• August 2008
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Exploratory, Anti-Anxiety, Social, And Sexual Behaviors Of Rats In Behavioral Estrus Is Attenuated With Inhibition Of 3α,5α-Thp Formation In The Midbrain Ventral Tegmental Area
The progesterone (P4) metabolite and neurosteroid, 5-pregnan-3-ol-20-one (3,5-THP) acts in the midbrain ventral tegmental area (VTA) to modulate lordosis of…
Read on PubMed• June 2008
