Featured Publications
Smartphone-Based Machine Learning Model for Real-Time Assessment of Medical… Smartphone-Based Machine Learning Model for…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue,…
We developed a machine learning model to perform binary classification of smartphone images of kidney biopsy tissue, based on the amount of cortex. The model was developed on smartphone images of 747 kidney biopsy cores from deceased donor kidneys,…
Cure Glomerulonephropathy Pathology Classification and Core Scoring Criteria,… Cure Glomerulonephropathy Pathology Classification…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD),…
Cure Glomerulonephropathy (CureGN) is an observational cohort study of patients with minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), membranous nephropathy (MN), or IgA nephropathy. We developed a conventional,…
Clinical and Histopathologic Characteristics of Pediatric Patients With Primary… Clinical and Histopathologic Characteristics of…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected…
Primary membranous nephropathy (PMN) is uncommon in children. Therefore, data on the clinical course of affected children are scarce. In recent years, several novel antigens have been implicated in the pathogenesis of PMN. However, the…
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.
All Publications
(478 Results)
-
18F-MK-6240 tau-PET In Genetic Frontotemporal Dementia
Tau is one of several proteins associated with frontotemporal dementia. While knowing which protein is causing a patient’s disease is…
Read on PubMed• June 2022
-
What Can Mercury Teach Us About Membranous Nephropathy and Minimal Change Disease?
From clinical associations of environmental exposure beginning with the story of cationic bovine serum in pediatric membranous nephropathy (MN) more…
Read on PubMed• June 2022
-
High-speed light-sheet microscopy for the in-situ acquisition of volumetric histological images of living tissue
Histological examinations typically require the excision of tissue, followed by its fixation, slicing, staining, mounting and imaging, with timeframes ranging…
Read on Nature• May 2022
-
Dual Diagnosis Of Histiocytoid Sweet Syndrome And Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
Histiocytoid Sweet syndrome (H-SS) is a rare variant of acute febrile neutrophilic dermatosis. It isfrequently associated with hematologic malignancies but…
Read on JAAD• May 2022
-
Collapsing Glomerulopathy In A Patient With Mixed Connective Tissue Disease
Collapsing glomerulopathy (CG) is a form of podocytopathy that is challenging to manage. CG can be idiopathic or associated with…
Read on PubMed• April 2022
-
6,5-Fused Ring, C2-Salvinorin Ester, Dual Kappa And Mu Opioid Receptor Agonists As Analgesics Devoid Of Anxiogenic Effects
Current common analgesics are mediated through the mu or kappa opioid receptor agonism. Unfortunately, selective mu or kappa receptor agonists…
Read on PubMed• April 2022
-
High-Speed Light-Sheet Microscopy For The In-Situ Acquisition Of Volumetric Histological Images Of Living Tissue
Histological examinations typically require the excision of tissue, followed by its fixation, slicing, staining, mounting and imaging, with timeframes ranging…
Read on PubMed• March 2022
-
Ext1 And Ncam1-Associated Membranous Lupus Nephritis In A Cohort Of Patients Undergoing Repeat Kidney Biopsies
EXT1/2 and NCAM1 associated membranous lupus nephritis (MLN) may represent distinct disease phenotypes with prognostic significance.
Read on PubMed• March 2022
-
Cell Type-Specific Mechanistic Target Of Rapamycin-Dependent Distortion Of Autophagy Pathways In Lupus Nephritis
Pro-inflammatory immune system development, metabolomic defects, and deregulation of autophagy play interconnected roles in driving the pathogenesis of systemic lupus…
Read on PubMed• March 2022
-
Cubilin And Amnionless Protein Are Novel Target Antigens in Anti–Brush Border Antibody Disease
The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the…
Read on Kidney International• March 2022
