October 22, 2020
Sarcoidosis in a Skeletal Muscle Biopsy
These images show skeletal muscle from the thigh of an African-American patient with muscle weakness and elevated CPK levels. Occasional well-formed non-caseating granulomota with mild surrounding chronic lymphoid inflammation are present. These morphologic findings are consistent with the presence of granulomatous myositis, and compatible with sarcoidosis: clinical correlation is required. (hematoxylin and eosin stained frozen section 100x and 200x magnification).