Back to Blog

Twitter Poll (July 7, 2021)

Joel Murphy, MD
By Joel Murphy, MD

Jul 08, 2021

ALECT2 amyloidosis, or leukocyte chemotactic factor 2 amyloidosis makes up less than 10% of all cases of renal amyloidosis

Answer: D, ALEC2

ALECT2 amyloidosis, or leukocyte chemotactic factor 2 amyloidosis makes up less than 10% of all cases of renal amyloidosis. This form of amyloidosis is classically seen in older individuals (~60 yrs.) and primarily affects individuals of Hispanic ancestry. Interestingly, while this form can be seen within glomeruli and vessels, it tends to have a propensity for interstitial deposition predominately within the cortex with sparing of the medulla. For more information, please see the following reference:

 

Larsen CP, Kossmann RJ, et al.  Clinical, Morphologic, and Genetic Features of Renal Leukocyte Chemotactic Factor 2 Amyloidosis Kidney Int 2014;2:378-82.

Tags:

Quick note: This post is to be used for informational purposes only and does not constitute medical or health advice. Each person should consult their own doctor with respect to matters referenced. Arkana Laboratories assumes no liability for actions taken in reliance upon the information contained herein.