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Neuro Notes

T-tubular Network

Electron microscopy on a muscle biopsy with myopathic changes showed an incidental “waffle-like” structure within the sarcoplasm (see arrow).  This…

Neuro Notes

Intranuclear Cytoplasmic Pseudoinclusion

This 55 year-old patient presented with generalized muscle weakness and normal CPK. Which of the following does the electron microscopic image…

Nemaline Rods, neuro notes, neuropathology, Dr. Mrachek
Neuro Notes

Nemaline Rods

What are these dark (osmophilic) structures seen in this electron micrograph of skeletal muscle? These osmophilic structures are Nemaline rods (largest,…

By Kelly Mrachek, MD