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Neuro Notes

T-tubular Network

Electron microscopy on a muscle biopsy with myopathic changes showed an incidental waffle-like structure within the sarcoplasm (see arrow). This…

Neuro Notes

Intranuclear Cytoplasmic Pseudoinclusion

This 55 year-old patient presented with generalized muscle weakness and normal CPK.   Which of the following does the electron…

Nemaline Rods, neuro notes, neuropathology, Dr. Mrachek
Neuro Notes

Nemaline Rods

What are these dark (osmophilic) structures seen in this electron micrograph of skeletal muscle?   These osmophilic structures are Nemaline…

By Kelly Mrachek, MD