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Neuro Notes

End-stage nerve

Clinical History:This 45-year-old patient underwent sural nerve biopsy to evaluate for potential etiologies of their progressive sensorimotor predominantly axonal polyneuropathy.…

Figure 1: Toluidine blue stained thick section 600x original magnification
Neuro Notes

Nerve Twig

Clinical historyThis 60-year-old patient presented with proximalmuscle weakness and pain of one-month’s duration.  Laboratory studies showed elevated CPK (~12000).Question:Which of…

Peripheral nerve axons
Neuro Notes

Peripheral Nerve Axons

Peripheral Nerve AxonsThis 60-year-old patient underwent sural nerve biopsy to evaluate for neuropathy.Do the numerous very small punctate areas of…


Diabetic, Neuropathy In A Diabetic Patient
Neuro Notes

Neuropathy In A Diabetic Patient

This patient presented with a multiple-year history of progressively worsening numbness and tingling which began in their feet and progressed…