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Thrombotic Microangiopathy
Art of Medicine

Art of Medicine: Thrombotic Microangiopathy

The above painting shows a glomerulus containing capillary loop fibrin thrombi, an arteriole with onion-skinning, and acute tubular injury, findings…

Acute kidney injury, anti-centromere antibodies, ischemia, schistoctes, scleroderma renal crisis, thrombotic microangiopathy, scleroderma
Teaching Points


The patient is a 32-year-old African American female who presents with hypertensive urgency, positive ANA, positive anti-RNA polymerase III antibody,…

Scleroderma in a renal biopsy at Arkana Laboratories
Diagnose This!

Diagnose This (August 27, 2018)

What is this finding and what is the likely etiology? …

By L. Nich Cossey, MD