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June 11, 2018

Diagnose This (June 11, 2018)

What is this finding and what is it classically associated with?

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This is an electron photomicrograph showing subepithelial, hump-shaped deposits. This finding is traditionally associated with infection-associated glomerulonephritis (especially post-Strep GN) which is still the most common etiology. However, it is important to understand that this finding is not entirely specific to infection and can rarely be seen in a range of kidney diseases (such as C3 glomerulonephritis).