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Case 4: A Polarizable Precipitate
Clinical presentation A 49-year-old male presents with acute deterioration in renal function. The serum creatinine is 4.5 mg/dL. He has…
Twitter Poll (September 12, 2019)
ANSWER: B, Necrotizing and Crescentic In a case series by Boils et al. which included 49 patients with GN due…
Twitter Poll (August 7, 2019)
ANSWER: D, AIN The most common finding on kidney biopsies in patients with immune checkpoint inhibitors (ICPIs)induced AKI is acute…
Type 1 Cryoglobulinemic Glomerulonephritis
The patient is a 75 year-old female who presents with proteinuria, a necrotic skin lesion on her lower extremity, and…
Art of Medicine: Collapsing Glomerulopathy
The above painting shows a glomerulus with capillary tuft collapse, visceral epithelial cell hyperplasia, and numerous protein resorption droplets within…
Diagnose This (June 24, 2019)
Immunofluorescence shows C3 (2-3+), IgM (1+), kappa (trace) and lambda (trace). What is your diagnosis? …
Light Chain Cast Nephropathy
A 75-year-old female is found to have a creatinine of 4.0 mg/dL on a routine laboratory examination. At the hospital,…
Disease Week: C3 Glomerulonephritis
Monday Rediscovery of Complement Mesangial C3 deposition only within the glomerulus has been reported since 1980. Only recognized recently as…
KDIGO Connections: Atypical Hemolytic-Uremic Syndrome
How do you treat patients with atypical hemolytic-uremic syndrome? Learn more about treatment and atypical hemolytic-uremic syndrome through KDIGO Connections!…
Art of Medicine: Lysozyme Nephropathy
The painting above shows acute tubular injury with numerous intracytoplasmic inclusions within proximal tubular epithelium, which can be seen in…
Scleroderma
The patient is a 32-year-old African American female who presents with hypertensive urgency, positive ANA, positive anti-RNA polymerase III antibody,…
Twitter Poll (April 3, 2019)
ANSWER: C IgAN is the most frequent diagnosis seen in kidney biopsies from patients with renal failure and history of…
Cryoglobulinemic Glomerulonephritis
The patient is a 60-year-old male who presents with proteinuria, hematuria, and a creatinine of 2.8 mg/dL. He was in…
Art of Medicine: ANCA-Associated Glomerulonephritis
The painting above shows a crescentic glomerulonephritis and necrotizing arteritis. A mixed interstitial inflammatory infiltrate is shown in the top…