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November 5, 2018

Diagnose This (November 5, 2018)

What renal state do these glomerular changes represent? 

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The photomicrograph shows glomerular tuft retraction with markedly corrugated glomerular basement membranes and periglomerular fibrosis. These findings are somewhat non-specific, but are often associated with kidney ischemia. In this case the patient had severe and uncontrolled hypertension with marked arteriosclerosis.