Featured Publications
About Our Research
We’ve doubled down on our commitment to research and teaching.
Arkana is a learning, teaching, and innovating practice with one unifying passion – to actively work toward the day that our research yields breakthroughs that make our services unnecessary. Eradicating rare and common diseases is the end game of all of our efforts because patient health is foremost in our minds every day. Read about some of our latest publications below.

All Publications
(479 Results)
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Endothelin-1 Upregulation Mediates Aging-Related Cardiac Fibrosis
Endothelin-1 (ET-1) plays a major role in regulating myocardial fibrosis in several pathological conditions, such as hypertension and diabetes.
Read on PubMed• January 2015
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Apolipoprotein L1-Associated Nephropathy And The Future Of Renal Diagnostics
Apolipoprotein L1 (APOL1)-associated nephropathies comprise a spectrum of related nondiabetic kidney diseases strongly associated with the G1 and G2 coding…
Read on PubMed• January 2015
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Didehydro-Cortistatin A Inhibits HIV-1 Tat Mediated Neuroinflammation And Prevents Potentiation Of Cocaine Reward In Tat Transgenic Mice
HIV-1 Tat protein has been shown to have a crucial role in HIV-1-associated neurocognitive disorders (HAND), which includes a group…
Read on NLM• January 2015
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Conditional Tat Protein Brain Expression In The GT-Tg Bigenic Mouse Induces Cerebral Fractional Anisotropy Abnormalities
Cerebral white matter changes including tissue water diffusion abnormalities detected with diffusion tensor magnetic resonance imaging (DTI) are commonly found…
Read on PubMed• January 2015
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Associations Of Brain Lesions At Autopsy With Polysomnography Features Before Death
To determine how sleep-disordered breathing, nocturnal hypoxia, and changes in sleep architecture in the elderly may be related to the…
Read on PubMed• January 2015
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B7-1 Immunostaining In Proteinuric Kidney Disease
B7-1–Positive proteinuric kidney disease is a recently described subcategory of primary podocytopathy in which immunostaining is reported to detect B7-1…
Read on PubMed• December 2014
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Tumor Grade Of Clear Cell Renal Cell Carcinoma Assessed By Contrast-Enhanced Computed Tomography
The purpose of this study was to clarify the association between CT findings and Fuhrman grade of clear cell renal…
Read on PubMed• November 2014
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Defining The Spectrum Of Immunoglobulin A-Dominant/Codominant Glomerular Deposition In Diabetic Nephropathy
In patients with diabetic nephropathy (DN), the spectrum of immunoglobulin A (IgA)-dominant/codominant glomerular deposition (IgAGD) has not been addressed in…
Read on PubMed• November 2014
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Isolated Endarteritis And Kidney Transplant Survival: A Multicenter Collaborative Study
Isolated endarteritis of kidney transplants is increasingly recognized. Notably, microarray studies revealed absence of immunologic signatures of rejection in most…
Read on PubMed• November 2014
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Effects Of Multiple Genetic Loci On Age At Onset In Late-Onset Alzheimer Disease: A Genome-Wide Association Study
Because APOE locus variants contribute to risk of late-onset Alzheimer disease (LOAD) and to differences in age at onset (AAO),…
Read on PubMed• November 2014
